Protein Alignment F9 and Sp212

DIOPT Version :10

• Sequence 1: NP_000124.1
• Gene: F9 / 2158
• HGNCID: 3551
• Length: 461
• Species: Homo sapiens
• Sequence 2: NP_996209.2
• Gene: Sp212 / 2768666
• FlyBaseID: FBgn0053329
• Length: 516
• Species: Drosophila melanogaster
• Alignment Length: 308
• Identity: 88/308 - (28%)
• Similarity: 146/308 - (47%)
• Gaps: 46/308 - (14%)

Human   172 PAVPFPCGRVSVSQTSKLTRAETVFPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKPG 236
            |.:|.|...|:|...:.        |...:...::..:::.....||..|     :|.|.:...|
  Fly   235 PPLPTPPAVVTVPPATP--------PPQRFDPRSQISSVVCGREGSTTPF-----IVRGNEFPRG 286

Human   237 QFPW-QVVLNGKVDAF---CGGSIVNEKWIVTAAHCVE--TGVKITVVAGEHNIEE-TEHTEQKR 294
            |:|| ..|.:.:|.|.   |.||:::...:::|||||.  |..::.|..|.::::: .|...:.|
  Fly   287 QYPWLSAVYHKEVRALAFKCRGSLISSSIVISAAHCVHRMTEDRVVVGLGRYDLDDYGEDGAEMR 351

Human   295 NVIRIIPHHNYNAAINKYNH-DIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGR 358
            ||:|::.|.:||.  ..|:. ||||:.::.|:..|..:.|||:...|.:.....  :|:::||||
  Fly   352 NVMRLLWHPDYNT--RSYSDADIALITIERPVTFNDIIAPICMWTVEASRTVST--TGFIAGWGR 412

Human   359 VFHKGRSALVLQYLRV-------PLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHV 416
            .....|:    ||.||       |.|..:| .|.|..|  ....||| :..|...|.|||||..:
  Fly   413 DEDSSRT----QYPRVVEAEIASPTVCAST-WRGTMVT--ERSLCAG-NRDGSGPCVGDSGGGLM 469

Human   417 TEVEGTSFLTGIISWGEE-----CAMKGKYGIYTKVSRYVNWIKEKTK 459
            .:......|.||:|.||.     |.: .:|.:|..:|:::|||.|..:
  Fly   470 VKQGDRWLLRGIVSAGERGPAGTCQL-NQYVLYCDLSKHINWISENIR 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:464251
		Tryp_SPc	227..457	CDD:238113	78/249 (31%)
Sp212	NP_996209.2	GD_N	23..127	CDD:464985
		Tryp_SPc	277..514	CDD:238113	78/249 (31%)