DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Slc36a3 and CG32081

DIOPT Version :9

Sequence 1:	NP_758462.2	Gene:	Slc36a3 / 215332	MGIID:	2665001	Length:	477	Species:	Mus musculus
Sequence 2:	NP_729646.1	Gene:	CG32081 / 326194	FlyBaseID:	FBgn0052081	Length:	471	Species:	Drosophila melanogaster

Alignment Length:	443	Identity:	128/443 - (28%)
Similarity:	216/443 - (48%)	Gaps:	49/443 - (11%)

- Green bases have known domain annotations that are detailed below.

Mouse    44 RREADALMFIQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHL 108
            |..|..:..|..|..|||..:|||.:.:||:...||::.|.:.|:::..:.:|.|.:|:.|....
  Fly    13 RNVAHPISDIGAFFSLLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVCFMLIHGMQMLIICMIEC 77

Mouse   109 TQRLQRSFVNYEETTMYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFLADNLQQIM 173
            ::|:|..:..|....:||.:..|. :.:..|..|||:|..:|..:|.|.|.||.:|:|..|:|::
  Fly    78 SRRMQIGYATYPVAMVYSFDQGPR-FFKYISKAGRYIVDGVLAFSQFGVCVVYNVFVAATLKQLV 141

Mouse   174 EEAHFTSNVCQPRQSLVMTSILDTRFYMLTILPFLILLVLIQNPQVLSIFSTLATITTLSSLALI 238
            :               ....:.|.|.|:..|...||....|:..:.|..|:.||:|...:..:|:
  Fly   142 D---------------FYWVVADLRIYIAVIALCLIPPFQIRKLKYLVPFNILASILIYTGFSLM 191

Mouse   239 FEYLIQTPHHSNLPLVANWKTFL-------LFFGTAIFTFEGVGMVLPLKSQMKSPQQFPAVLYL 296
            ..||.     .:||.:.......       ||||.|:|:...||::|.:::.|..|:.     ||
  Fly   192 MYYLF-----VDLPPITERNILFGRIDKIPLFFGIALFSITSVGVMLAVEATMAKPRH-----YL 246

Mouse   297 G--------MSFVIFLYICLGTLGYMKFGTDTQASITLNLPIC-WLYQSVKLMYSVGIFFTYALQ 352
            |        :..||..|:..|.:||.::|.:|..||:||:|.. .|.|..|...:..||.||.|.
  Fly   247 GWFGILDRAILLVIISYVTFGLMGYWRYGDETAGSISLNIPTDEVLSQVAKGFIAAAIFLTYPLA 311

Mouse   353 FHVPAEIIVPYVVSRVSE--NWALFVDLTVRTALVCLTCFSAVLIPRLDLVISLVGSVSSSALAI 415
            ..|..:||:.:..::..:  |.|| .:..:|...|.|.|.:|::.|.|..::||||:::.|.|.:
  Fly   312 GFVIIDIIMNHFWNKNGDLPNAAL-KESILRACTVVLICITAIIAPNLGPLLSLVGALTISLLNL 375

Mouse   416 IIPPLLEIATFYSENISCA----TIVKDIMISILGLLGCVLGTYQALYEMTQQ 464
            :.|.|:||..:|....:..    .:||||...|:|:|..|.||..::.:|..:
  Fly   376 VFPALIEICLYYPPEYNYGKLKWVLVKDIFYVIVGILILVQGTVFSIKDMISE 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slc36a3	NP_758462.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	19..43
Slc36a3	NP_758462.2	SLC5-6-like_sbd	52..458	CDD:382020	125/427 (29%)
CG32081	NP_729646.1	SLC5-6-like_sbd	17..422	CDD:294310	125/431 (29%)
CG32081	NP_729646.1	SdaC	20..415	CDD:223884	122/421 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849013
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940