Protein Alignment Myocd and Mrtf

DIOPT Version :10

• Sequence 1: XP_011247195.1
• Gene: Myocd / 214384
• MGIID: 2137495
• Length: 996
• Species: Mus musculus
• Sequence 2: NP_001137879.3
• Gene: Mrtf / 38338
• FlyBaseID: FBgn0052296
• Length: 1788
• Species: Drosophila melanogaster
• Alignment Length: 1308
• Identity: 261/1308 - (19%)
• Similarity: 420/1308 - (32%)
• Gaps: 488/1308 - (37%)

Mouse    44 SDLINVNECQALKGPTEFHDPRKQLDSAKTEDSLRRKGRNRSDRASLVTMHILQASTA--ERSIP 106
            |.|:......:||.....|:..|||:.|||.|.|:.|.:.|.:|..|..:|||:....  :.|:.
  Fly   356 SQLVEQGIIPSLKTSPAIHEQCKQLERAKTSDLLKAKIQQRPNREDLERLHILEEDECHIDPSLA 420

Mouse   107 TAQMKLKRARLADDLNEKIALRPGPLELVEKNILPMDSSVKEAIKGTEVSLSKAADAF------- 164
            ..|..||:|||||.||.:|..|||||||::||||..:..:::.:|...||....::..
  Fly   421 EKQRMLKKARLADQLNSQIQHRPGPLELIKKNILHTEKPIEKIVKEGLVSFKATSEGLLTRPQHP 485

Mouse   165 ----AFEDD--SSRDGLSPDQARSEDPQGSTGSTP-DIKSTEAP-----------------LDTI 205
                .|:||  ||.........|.::...:|.|:| |:....|.                 :.|.
  Fly   486 HSYVTFDDDSLSSESDTRQTPPRLDEAMVATSSSPTDVLQAAAASAGIVTMALTMPTAGQLVVTS 550

Mouse   206 QDLTPGSESDKNDAASQP-----------------------------------GNQSDP------ 229
            ..:.|..:..|......|                                   |..:.|
  Fly   551 PQILPQQQQPKAIVVPAPVPPPPPPPPPLPMASIIKVKQETANLYEELCQSVTGTTASPVNHLYS 615

Mouse   230 ------GKQVLGPLST-----PIPVHT--------AVKSKSLGDSKNRHKKPKDPKPKVKKLKYH 275
                  ....|.|||:     |.|:.|        :|||.:.|..|||.|....|..|.:.:|:|
  Fly   616 PCSLASSTSTLSPLSSIASPPPPPMTTTRLHLAPVSVKSDAPGKDKNRKKSKSKPVSKARTIKFH 680

Mouse   276 QYI-PPDQKAEK--SPPPMDSAYARLLQQQQLFLQ------------------------------ 307
            :|. ||....:|  ...|.:::|..:|:||...|:
  Fly   681 EYKGPPSAAGQKQDQTQPEETSYQLMLEQQNCLLKFLENLNKNQSIIPAPSAPGVMLPAAPGATN 745

Mouse   308 -------------------------------------------------------------LQIL 311
                                                                         |.::
  Fly   746 NSITVTTKTVPALASQSAPAPAPISLPNTISITSSSGGAPLNFGDATMLTPTPAATPTPPTLSLI 810

Mouse   312 SQQQQQQQQQQQQQQQQQQQQQRFSYPGMHQTHLKEPNEQMARNPNPSSTPLSNTPLSPVKNSIS 376
            :..|||.|..||.||..|..      |..|...|          |:|:.:..|:.|.||..:...
  Fly   811 AAPQQQLQLHQQHQQLHQPT------PVQHPPPL----------PSPALSVSSSIPPSPATSYAE 859

Mouse   377 GQT-GVSSLKPGPLPPNLDDLKVSELRQQLRIRGLPVSGTKTALVDRLRPF-----QDCAGNPVP 435
            ..| .::.|      ..|:.:|||:|:|.|:.|.|||||.|..|::||:|:     .|....|.|
  Fly   860 STTSSITDL------ARLEKMKVSDLKQHLKRRNLPVSGPKPHLIERLKPYLPLEPLDSNVTPAP 918

Mouse   436 NFGDITTVTFPVTPNTLPSYQSSPTGFYHFGSTSSSPPISPASSDLSAAGSLPDTFTDASPGFGL 500
            ...:..|     ||..:....:..|.  :.|.....||::...||.|......|.......
  Fly   919 TSNNSNT-----TPEVITISDAMDTS--NCGLLEQPPPVTMLVSDASMEHEQMDVVQQQMD---- 972

Mouse   501 HASPVPACTDESLLSSLNGGSGPSEPD--GLDSEKDKMLVEKQKVINQLTWKLRQEQRQVEELRM 563
            :..|:   |.:::|        |.:|.  .:....:::|.|:|:.|::|..:|::.|::::::|.
  Fly   973 NTHPM---TLQTIL--------PPQPQTATIILTNEELLREQQRKIDELQRQLQRSQQELQKIRQ 1026

Mouse   564 QLQKQKS------SCSDQKPLP----FLATTIKQEDVSSCPFAPQQ------------ASGKGQG 606
            :.|:|:.      :......||    .|.||.......:....|||            |:|....
  Fly  1027 RQQQQQHQQQQTVTAQVVNALPSQQITLITTTSNGPQQTLTVMPQQVEKNFPAKVTVKATGGNSN 1091

Mouse   607 H--------------------------SSDSPPP------------------------ACETAQL 621
            |                          ||.:|||                        |.:..|.
  Fly  1092 HKVNGLQQQGSAAKKPASSNSNSNSNISSSNPPPINQKMVVKQQLEAKIQKQKAAAAAAAQQQQQ 1156

Mouse   622 LPHCVESSGQTHVLSSTFLSPQCSPQHSPLGGLKSPQHISLPPSPNNHYFLASS-SGAQRENHGV 685
            .....:...|...|.......|...|...|  .:..|.:.:|.:.|||...||: :..::.|...
  Fly  1157 QQQQQQQQQQQQALQQQQQQQQQQQQVRLL--TQKTQTVFIPFNNNNHINNASAKTTTKKSNVPA 1219

Mouse   686 SSPSSSQGCAQNSGAHEGHSSSFSSPASSLHQPFS---------------GTQADSSHSAG---L 732
            ::.:::......:......:::.:||.:..|....               ..|..::|:.|   |
  Fly  1220 NNTNTTTATMMQAAKPAAVAAAAASPGNQHHNNLGLLWNEGNQTILLLGLNDQHMTAHTLGNISL 1284

Mouse   733 NPCPKSPSIHPKMTGLQSSDKVGP---------TFSIPSPTFSKSSSAVSDITQ----------- 777
            .....:.:..|..|.:.:|....|         |.|:||..|...:.::  |||
  Fly  1285 TATTTTTAAPPAATPVAASTIAPPKKILNGHQRTNSLPSIVFPIETKSI--ITQQQLQQLQQQQQ 1347

Mouse   778 ---------------------------PPSYEDAVKQ---------------------------- 787
                                       ||.||:|.||
  Fly  1348 QQQQFQPVQQPKQQQLNQVDIKPAPAPPPQYEEATKQLAASKAAALNGLLPLVKIKEEPVQSPAP 1412

Mouse   788 ----------------QMTRSQQMDELLDVLIESGEMPADAREDHSCLQKIPKIPGSSCSPTAIP 836
                            ...:|:|:.::||:||:.||:|..|     .|:.|          |.:.
  Fly  1413 SAAPLPQTAPLCKRKTASIKSEQVSDVLDILIKQGELPESA-----ALEPI----------TPLT 1462

Mouse   837 PKPSASFEQASSGGQMAFDHYANDSDEHLEVLLNSHSP---IGKVSDVTLL-KIGSEEPPFDSIM 897
            |.|..|                         :.|..:|   .|..|.|.|: |:.:...|..::
  Fly  1463 PLPELS-------------------------MFNGATPTTAAGGASIVPLVPKLETPVTPVQNL- 1501

Mouse   898 DGFPGKAAEDLFSAHELLPGPLSPMHA------QLSPPSVDSSGLQLSFTESPWETME-WLD--- 952
                 ..|.|....|.......:|.|.      ..||...|||.:.   .||..:|:: :|:
  Fly  1502 -----DVAMDTNVQHVGFASNQAPNHVFIESIDMASPLQTDSSAID---AESVAKTLDIFLEQHH 1558

Mouse   953 LTPPSSTP 960
            .|||.|||
  Fly  1559 ATPPPSTP 1566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myocd	XP_011247195.1	RPEL	119..144	CDD:128947	15/24 (63%)
		SAP	393..426	CDD:460424	17/32 (53%)
		KLF1_2_4_N	<569..690	CDD:425360	31/193 (16%)
Mrtf	NP_001137879.3	RPEL	387..412	CDD:128947	9/24 (38%)
		RPEL	433..458	CDD:128947	15/24 (63%)
		SAP	871..905	CDD:460424	18/33 (55%)