Protein Alignment Tfeb and Usf

DIOPT Version :9

• Sequence 1: NP_035679.3
• Gene: Tfeb / 21425
• MGIID: 103270
• Length: 534
• Species: Mus musculus
• Sequence 2: NP_572167.3
• Gene: Usf / 31384
• FlyBaseID: FBgn0029711
• Length: 437
• Species: Drosophila melanogaster
• Alignment Length: 394
• Identity: 71/394 - (18%)
• Similarity: 120/394 - (30%)
• Gaps: 161/394 - (40%)

Mouse   161 KFAAHVSPAQGSPKPA--------PAASPGVR--AGH---------------------VLSTSAG 194
            :|.:..|....|..|:        |.|.||:.  ..|                     :|::..|
  Fly    12 EFGSSTSNTNTSTSPSSVNISNANPTAGPGLMTITNHHTADLSEALVHSSFANGQQSLILTSDTG 76

Mouse   195 NSAPNSPMAMLHISSNPEKEFDD-----VIDNIMRLDSVLGYINP-EMQMPNTLPLSSSHLNVY- 252
            |...||..|.:.::...::..||     .|......|..:..:.| .:|:||.|.|.:. ..:|
  Fly    77 NPLMNSQGAQIFLTICGDENSDDSQEYYTIKQEPGCDLDIHSLLPSNLQLPNNLQLPTG-CEIYL 140

Mouse   253 -------SGDPQVTAS-------------MVGVTSSS---------------CPADLTQKRELTD 282
                   .|:|...|:             :..||:||               .|.::......|.
  Fly   141 VKETGSLMGEPPTKAAIKLELDTLSEKPLLPSVTTSSSTQSAVITAQTVNPPIPGNINTTTSTTS 205

Mouse   283 ----------------------AESRALAKER-----------QKKDN-----HNLIERRRRFNI 309
                                  |::|:..:..           :|:|:     ||.:|||||..|
  Fly   206 TTTTTSVLYGSHGNGHGHGHAHAQARSQPESAGQTPSSKLEAYKKRDDKRRATHNEVERRRRDKI 270

Mouse   310 NDRIKELGMLIPK----------------------------------------ANDLDVRWNKGT 334
            |..|.:|..::|.                                        .||     :|..
  Fly   271 NSWIFKLKEMLPSLSSSSSFSEASTSPSTSGSTSTNGSSHSKGNASSSSGRAPPND-----SKSQ 330

Mouse   335 ILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQEL----EMQARVHGLPTTSPSGVN 395
            ||..:.:||:.||.::...|:....:..|..:|:.|...:..|    ::|.|.|.....|...|.
  Fly   331 ILIKACEYIKSMQGEIDTLRDCLRETDSLRASNQALREELDRLKRQQQLQERFHTAGGRSTFNVT 395

Mouse   396 MAEL 399
            :..|
  Fly   396 LNSL 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tfeb	NP_035679.3	MITF_TFEB_C_3_N	63..219	CDD:292573	17/93 (18%)
		HLH	291..351	CDD:238036	23/115 (20%)
		DUF3371	379..531	CDD:288684	6/21 (29%)
Usf	NP_572167.3	HLH	255..343	CDD:278439	19/92 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1708
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840