DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tbxas1 and Cyp6a20

DIOPT Version :9

Sequence 1:NP_035669.3 Gene:Tbxas1 / 21391 MGIID:98497 Length:533 Species:Mus musculus
Sequence 2:NP_611002.3 Gene:Cyp6a20 / 36664 FlyBaseID:FBgn0033980 Length:501 Species:Drosophila melanogaster


Alignment Length:540 Identity:154/540 - (28%)
Similarity:263/540 - (48%) Gaps:69/540 - (12%)


- Green bases have known domain annotations that are detailed below.


Mouse    16 VTVTLLVALLALLKWYSMSAFSRLEKLGIRHPKPSPFVGN------LMFFRQGFWESQLELRERY 74
            |.:.||:.::..:.||....|:..::.||.|.:|....||      .:.|...|..:..:||.:.
  Fly     3 VMIVLLIGVITFVAWYVHQHFNYWKRRGIPHDEPKIPYGNTSELMKTVHFADIFKRTYNKLRNKT 67

Mouse    75 -GPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNRMASGL------EPKMVADSVLLLRDRRW 132
             ||..|:|:..:..||:::.|..|.||:..|..|.:|   |:      :|  ::.:::.:..::|
  Fly    68 DGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDR---GVFHNERDDP--LSANLVNIDGQKW 127

Mouse   133 EEVRGALMSSFSPEKLDEMTP-LISQACELLVAHLKRYAASRDAFNIQRCYCCYTIDVVASVAFG 196
            :.:|..|..:|:..|:..|.| :::...||:....:..:|..|:..|......:|.||:.|.|||
  Fly   128 KTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETASADSDSMEITNVVARFTADVIGSCAFG 192

Mouse   197 TQVDSQNSPEDPFVQHCRRASTFCIP-----RPLLVLILSFPSIMVPLARILPNKNRDELNGFFN 256
            ....|.:.|:..|||    ..|..|.     :.:.:|:...|.:   .|::.......|:..|:.
  Fly   193 LDCHSLSDPKAKFVQ----MGTTAITERRHGKSMDLLLFGAPEL---AAKLRMKATVQEVEDFYM 250

Mouse   257 TLIRNVIALRDQQAAEERRRDFLQMVLDAQHSMNSVGVEGFDMVPESLSSSECTKEPPQRCHPTS 321
            .:||:.:..|.:.  ..:|.||:.|:::.:                 |......||         
  Fly   251 NIIRDTVDYRVKN--NVKRHDFVDMLIEMK-----------------LKFDNGDKE--------- 287

Mouse   322 TSKPFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLFMGKHPAP-EYHS 385
              ...|.:||..|||:|.:||.|..:.|:.|..|.||.|.|.|::|..|::..:.:|... :|.|
  Fly   288 --NGLTFNEIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLKQHNGKLDYDS 350

Mouse   386 LQEGLPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQR--IPAGTVLEIAVGALHHDPEHWPNP 448
            ::| :.||:.||.||:|..|......|.|.|..:....:  |..||.:.:...|:|||||.:|.|
  Fly   351 MRE-MTYLEKVIDETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDPEFYPEP 414

Mouse   449 ETFDPERFTAEARLQRRP-FTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFEASP-ETQVP 511
            |.|.||||. |.::|:|| .|:||||.|||:|:|:|.|.:.|.:.:..::|.|:||..| :|.||
  Fly   415 EKFIPERFD-EDQVQQRPACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFEFHPTKTVVP 478

Mouse   512 LQLESKS-ALGPKNGVYIKI 530
            |:..:.. .|..|.|:::|:
  Fly   479 LEYRTDDFLLSSKGGIHLKV 498

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tbxas1NP_035669.3 p450 47..528 CDD:365848 144/505 (29%)
Cyp6a20NP_611002.3 p450 32..496 CDD:278495 145/507 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0158
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H130979
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D264519at33208
OrthoFinder 1 1.000 - - FOG0000037
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100014
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X40
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
87.720

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