Protein Alignment Tbxas1 and Cyp6a19

DIOPT Version :10

• Sequence 1: NP_035669.3
• Gene: Tbxas1 / 21391
• MGIID: 98497
• Length: 533
• Species: Mus musculus
• Sequence 2: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 141/540 - (26%)
• Similarity: 262/540 - (48%)
• Gaps: 70/540 - (12%)

Mouse    16 VTVTLLVALLALLKWYSMSAFSRLEKLGIRHPKPSPFVGNLMFFRQGFWESQ----------LEL 70
            :.:.|:|.:|.|:.|:.:..::..::.||.|..|:..:||    ....|.:.          |:.
  Fly     3 ILLGLVVGVLTLVAWWVLQNYTYWKRRGIPHDPPNIPLGN----TGELWRTMPLAGILKRTYLKF 63

Mouse    71 RERY-GPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNR-MASGLEPKMVADSVLLLRDRRWE 133
            |::. ||..|:||....::||::.|.:|.||:.:|..|.:| :....:...:.:::..:..::|:
  Fly    64 RKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTNNLATIEGQKWK 128

Mouse   134 EVRGALMSSFSPEKLDEM-TPLISQACELLVAHLKRYAASRDAFNIQRCYCCYTIDVVASVAFGT 197
            .:|..|..:|:..|:..| :.:::...|::....::.::|.....:......:|.||:...|||.
  Fly   129 NLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFTSDVIGICAFGL 193

Mouse   198 QVDSQNSPEDPFVQ------HCRRASTFCIPRPLLVLILSFPSIMVPLA--RILPNKNRDELNGF 254
            :.:|...|:..|||      ..||....     :.:||...|.:.|.|.  .:||:..:     |
  Fly   194 KCNSLRDPKAEFVQMGYSALRERRHGWL-----VDLLIFGMPKLAVKLGFQFLLPSVQK-----F 248

Mouse   255 FNTLIRNVIALRDQQAAEERRRDFLQMVLDAQHSMNSVGVEGFDMVPESLSSSECTKEPPQRCHP 319
            :..::::.|..|.::  :..|.||:..::|.:                            |:...
  Fly   249 YMKIVQDTIDYRMKR--KVTRNDFMDTLIDMK----------------------------QQYDK 283

Mouse   320 TSTSKPFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLFMGKHPAP-EY 383
            .........:|:..|||:|.:||.|..:.|:.|..|.||.:.|.|::|..|:|..:.::... ||
  Fly   284 GDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEY 348

Mouse   384 HSLQEGLPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQR--IPAGTVLEIAVGALHHDPEHWP 446
            .|:|: |.|::.||:|:||.:|......|.|.:..:....:  |.|||.:.::...:|||||.:|
  Fly   349 DSMQD-LFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYP 412

Mouse   447 NPETFDPERFTAEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFEASPETQVP 511
            .||.|.||||..|...:|....:||||||||:|:|:|.|.:.|.:.:..::|.||||..|:|.||
  Fly   413 EPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVP 477

Mouse   512 LQLE-SKSALGPKNGVYIKI 530
            ::.. :...||.:.|:::.|
  Fly   478 MKYTINNLLLGSEGGIHLNI 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbxas1	NP_035669.3	cytochrome_P450	74..527	CDD:477761	126/467 (27%)
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	126/467 (27%)