DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Tbxas1 and Cyp6a13

DIOPT Version :9

Sequence 1:NP_035669.3 Gene:Tbxas1 / 21391 MGIID:98497 Length:533 Species:Mus musculus
Sequence 2:NP_610390.1 Gene:Cyp6a13 / 35837 FlyBaseID:FBgn0033304 Length:493 Species:Drosophila melanogaster


Alignment Length:539 Identity:163/539 - (30%)
Similarity:266/539 - (49%) Gaps:82/539 - (15%)


- Green bases have known domain annotations that are detailed below.


Mouse    15 IVTVTLLVALLALLKWYSMSAFSRLEKLGIRHPKPSPFVGNLMFFRQGFWESQLELR-------- 71
            :.||.||  |...|:|:    :|...:.|:...:|..|.||:....:....:.:.||        
  Fly     8 VFTVGLL--LYVKLRWH----YSYWSRRGVAGERPVYFRGNMSGLGRDLHWTDINLRIYRKFRGV 66

Mouse    72 ERYGPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNR-MASGLEPKMVADSVLLLRDRRWEEV 135
            |||   |||:......:.|.:.::|:.:::.:||:|::| :...:....:..::|.|....|..:
  Fly    67 ERY---CGYFTFMTKSLFIMDLELIRDIMIRDFSSFADRGLFHNVRDDPLTGNLLFLDGPEWRWL 128

Mouse   136 RGALMSSFSPEKLDEMTP-------LISQACELLVAHLKRYAASRDAFNIQRCYCC-YTIDVVAS 192
            |..|...|:..|:..|.|       .::|||.|.|..::    ::|       .|. :|.||:.|
  Fly   129 RQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQVGEIE----AKD-------LCARFTTDVIGS 182

Mouse   193 VAFGTQVDSQNSPEDPFVQHCRRASTFCIPRPL-LVLILSFPSIMVPLARILPNK-NRDELNGFF 255
            .|||.:.:|...||..|    ||........|| .||:.:|......|||.|..: .|.|::.||
  Fly   183 CAFGLECNSLQDPESQF----RRMGRSVTQEPLHSVLVQAFMFAQPELARKLRFRLFRPEVSEFF 243

Mouse   256 NTLIRNVIALRDQQAAEERRRDFLQMVLDAQHSMNSVGVEGFDMVPESLSSSECTKEPPQRCHPT 320
            ...:|..:..|.::  ...|.|.:|::::       :|.||   |.::||               
  Fly   244 LDTVRQTLDYRRRE--NIHRNDLIQLLME-------LGEEG---VKDALS--------------- 281

Mouse   321 STSKPFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLFMGKHPAP-EYH 384
                   .::|..||.:|.:||.:..:.|:||..|.||.:||.||||..||...:.::... .|.
  Fly   282 -------FEQIAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVLAVLKRNNQKLTYD 339

Mouse   385 SLQEGLPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQR--IPAGTVLEIAVGALHHDPEHWPN 447
            |:|| :||||.|::||||.||......|.:.::.::....  :..|:.:.|.|.::|||||.:|:
  Fly   340 SVQE-MPYLDQVVAETLRKYPILPHLLRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELYPD 403

Mouse   448 PETFDPERFTAEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFEASPETQVPL 512
            ||.|||.||..|....|.||.|||||.|||:|:|.|.|.|.||:.::.:|..|:|..|.:||:||
  Fly   404 PEKFDPSRFEPEEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSEKTQIPL 468

Mouse   513 QLESKSAL-GPKNGVYIKI 530
            :..|::.| ..:.||::::
  Fly   469 KFSSRNFLISTQEGVHLRM 487

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tbxas1NP_035669.3 p450 47..528 CDD:365848 154/503 (31%)
Cyp6a13NP_610390.1 p450 33..476 CDD:278495 151/495 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0158
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D264519at33208
OrthoFinder 1 1.000 - - FOG0000037
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100014
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X40
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
76.720

Return to query results.
Submit another query.