DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tbxas1 and Cyp6a14

DIOPT Version :9

Sequence 1:NP_035669.3 Gene:Tbxas1 / 21391 MGIID:98497 Length:533 Species:Mus musculus
Sequence 2:NP_001286199.1 Gene:Cyp6a14 / 35835 FlyBaseID:FBgn0033302 Length:509 Species:Drosophila melanogaster


Alignment Length:543 Identity:160/543 - (29%)
Similarity:259/543 - (47%) Gaps:65/543 - (11%)


- Green bases have known domain annotations that are detailed below.


Mouse    15 IVTVTLLVALLALLKWYSMSAFSRLEKLGIRHPKPSPFVGNL--MFFRQGFWESQLELRERY--- 74
            :.|:.|:..:|.|.....:..||..::.|:.|..|.|.|||:  :..:..|.:....:.:::   
  Fly     2 LFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPIVGNMRGIVKKYHFRDINQRIYKKFKGQ 66

Mouse    75 GPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNRMA-SGLEPKMVADSVLLLRDRRWEEVRGA 138
            ||:.|.|:..:...:|::.|.||||::::||.|.:|.| :......:...:..|....|..:|..
  Fly    67 GPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTGHLFALEGEEWRAMRHK 131

Mouse   139 LMSSFSPEKLDEMTPLI-------SQACELLVAHLKRYAASRDAFNIQRCYCC--YTIDVVASVA 194
            |...|:..|:.:|:.:|       ..|.:..|..     |..:..|::....|  :|.||:.|.|
  Fly   132 LTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKE-----AKVEEGNVEIKDLCARFTTDVIGSCA 191

Mouse   195 FGTQVDSQNSPEDPFVQHCRRASTFCIPRPLLVLILSFPSIMVPLAR-----ILPNKNRDELNGF 254
            ||.:.:|...|...|.|..|...|   .|....|:.||......|||     :||    |:|..|
  Fly   192 FGLECNSLQDPSAEFRQKGREIFT---RRRHSTLVQSFIFTNARLARKLRIKVLP----DDLTQF 249

Mouse   255 FNTLIRNVIALRDQQAAEERRRDFLQMVLD--AQHSMNSVGVEGFDMVPESLSSSECTKEPPQRC 317
            |.:.::|.:..|.:...  :|.||::.:::  |:....:...:|.|:                  
  Fly   250 FMSTVKNTVDYRLKNGI--KRNDFIEQMIELRAEDQEAAKKGQGIDL------------------ 294

Mouse   318 HPTSTSKPFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLFMGKHPAPE 382
                 |...|::::..|||:|.:||.|..::|:|...|.||..||.|:||.:|::..:......|
  Fly   295 -----SHGLTLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGE 354

Mouse   383 --YHSLQEGLPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQRI--PAGTVLEIAVGALHHDPE 443
              |..|.: :.|||.|:|||||.:|......||..:|.::....|  ..|.:..|.|..:|||||
  Fly   355 LNYDVLAQ-MTYLDQVLSETLRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPE 418

Mouse   444 HWPNPETFDPERFTAEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFEASPET 508
            .:|.||.|||.||..|....|.|..|||||.|||:|:|:|.|.:..|:.::.:|.:|:|..|..|
  Fly   419 IYPEPEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRT 483

Mouse   509 QVPLQLESKSALGPKN-GVYIKI 530
            .|||....||.|...| |:|:|:
  Fly   484 DVPLIFSKKSFLLTTNDGIYLKV 506

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tbxas1NP_035669.3 p450 47..528 CDD:365848 150/507 (30%)
Cyp6a14NP_001286199.1 p450 32..506 CDD:306555 152/511 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D264519at33208
OrthoFinder 1 1.000 - - FOG0000037
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100014
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2429
SonicParanoid 1 1.000 - - X40
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
76.850

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