DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Tbxas1 and Cyp28a5

DIOPT Version :9

Sequence 1:NP_035669.3 Gene:Tbxas1 / 21391 MGIID:98497 Length:533 Species:Mus musculus
Sequence 2:NP_609694.1 Gene:Cyp28a5 / 34817 FlyBaseID:FBgn0028940 Length:505 Species:Drosophila melanogaster


Alignment Length:559 Identity:127/559 - (22%)
Similarity:235/559 - (42%) Gaps:103/559 - (18%)


- Green bases have known domain annotations that are detailed below.


Mouse    14 TIVTVTLLVALL-ALLKWYSMSAFSRLEKLGIRHPKPSPFVGNL--MFF--RQGFWESQ---LEL 70
            |:..|:|:|.|| |:|.|    .:....|.|:..|||....||.  ||.  |...::..   .:.
  Fly     5 TLTLVSLVVGLLYAVLVW----NYDYWRKRGVPGPKPKLLCGNYPNMFTMKRHAIYDLDDIYRQY 65

Mouse    71 RERYGPLCGYYLGRRMHVVISEPDMIKQVLVENFSNF-SNRMASGLEPK---MVADSVLLLRDRR 131
            :.:|..: |.:..|...:::..|.:.::|.|.||.|| .|.:|..::.|   :.|::...|...:
  Fly    66 KNKYDAV-GIFGSRSPQLLVINPALARRVFVSNFKNFHDNEIAKNIDEKTDFIFANNPFSLTGEK 129

Mouse   132 WEEVRGALMSSFSPEKLDEMTPLISQACELLVAHLKRY--AASRDAFNIQRCYCCYTIDVVASVA 194
            |:..|..:....:..::..:.|:.::.|:.|...:::.  ..|:|..:.:....|:|.::|....
  Fly   130 WKTRRADVTPGLTMGRIKTVYPVTNKVCQKLTEWVEKQLRLGSKDGIDAKHMSLCFTTEMVTDCV 194

Mouse   195 FGTQVDSQNSPEDPFVQHC----RRASTFCIPRPLLVLILSFPSI--MVPLARILPNKNRDELNG 253
            .|...:|.:....|.:...    .:..||.:   ..:|..||||:  ::.| |.:|    .::..
  Fly   195 LGLGAESFSDKPTPIMSKINDLFNQPWTFVL---FFILTSSFPSLSHLIKL-RFVP----VDVER 251

Mouse   254 FFNTLIRNVIALRDQQAA---EERRRDFLQMVLDAQHSMNSVGVEGFDMVPESLSSSECTKEPPQ 315
            ||..|:.:.:..|..|.|   :..|.|||..:|......|                         
  Fly   252 FFVDLMGSAVETRRAQLAAGKQFERSDFLDYILQLGEKRN------------------------- 291

Mouse   316 RCHPTSTSKPFTVD--EIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLFMGKH 378
                        :|  :::..:..||:.|.|.....|:.|...|..:.:.|..|.:|:       
  Fly   292 ------------LDNRQLLAYSMTFLLDGFETTATVLAHILLNLGRNKEAQNLLREEI------- 337

Mouse   379 PAPEYHSLQEG---------LPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQRIP-----AGT 429
               ..| ||:|         |||||..:.||:|::||.|...:...:..|:..:..|     .||
  Fly   338 ---RSH-LQDGTIAFEKLSDLPYLDACVQETIRLFPPGFMSNKLCTESIEIPNKEGPNFVVEKGT 398

Mouse   430 VLEIAVGALHHDPEHWPNPETFDPERFTA--EARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLT 492
            .:.:.......|.|.:|||::|.||||..  .|:..|....::.||.|||.|:|:|...:.:|..
  Fly   399 TVVVPHYCFMLDEEFFPNPQSFQPERFLEPDAAKTFRERGVFMGFGDGPRVCIGMRFATVQIKAA 463

Mouse   493 ILQVLHKFRFEASPETQVPLQLESKSAL-GPKNGVYIKI 530
            |::::.||..:.:.:|:.....|....: |.:.|:::.:
  Fly   464 IVELISKFNVKINDKTRKDNDYEPGQIITGLRGGIWLDL 502

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tbxas1NP_035669.3 p450 47..528 CDD:365848 116/521 (22%)
Cyp28a5NP_609694.1 p450 33..500 CDD:299894 116/523 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0158
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D264519at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X40
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
65.780

Return to query results.
Submit another query.