DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tbxas1 and Cyp6a16

DIOPT Version :9

Sequence 1:NP_035669.3 Gene:Tbxas1 / 21391 MGIID:98497 Length:533 Species:Mus musculus
Sequence 2:NP_001285631.1 Gene:Cyp6a16 / 19836250 FlyBaseID:FBgn0031726 Length:500 Species:Drosophila melanogaster


Alignment Length:539 Identity:161/539 - (29%)
Similarity:264/539 - (48%) Gaps:75/539 - (13%)


- Green bases have known domain annotations that are detailed below.


Mouse    17 TVTLLVALLALLKWYSMSAFSRLEKLGIRHPKPSPFVGNLMFFR-QGFWESQLELRERY------ 74
            |:.||.:||:.|..|....|:..|..||...:|....|:  ||| |....|:| |:|.|      
  Fly     4 TLLLLTSLLSFLLGYLRYRFTYWELRGIPQLRPHFLFGH--FFRLQSVHYSEL-LQETYDAFRGS 65

Mouse    75 GPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNRMASGLEPKMVADSVLLLRDRRWEEVRGAL 139
            ..:.|.|:..|...|:.:.|::|.||:.:|:||.:|.:...:|  :..::..|:...|..:|..|
  Fly    66 AKVAGTYVFLRPMAVVLDLDLVKAVLIRDFNNFVDRRSFHGDP--LTANLFNLQGEEWRNLRTKL 128

Mouse   140 MSSFSPEKLDEMTPLISQACELLVAHLKRYAASRDA-FNIQRCYCCYTIDVVASVAFGTQVDSQN 203
            ..:|:..|:..|...:|...:.|.........|:.| ..:......||.||:.|.||||:..|..
  Fly   129 SPTFTSGKMKYMFGTVSTVAQQLGGTFDELVGSQGAVLELHDLMARYTTDVIGSCAFGTECSSLR 193

Mouse   204 SPEDPFVQHCRRA---STFCIPRPL--LVLILSFPSIMVPLARILPNKNRDELNGFFNTLIRNVI 263
            .|:..|.|..||.   |...|...:  :..:.|...:.:|: |||    ..::..|||.::|..:
  Fly   194 EPQAEFRQVGRRIFRNSNRSIRWRIFKMTYLSSLAKLGLPV-RIL----HPDITKFFNRIVRETV 253

Mouse   264 ALRDQQAAEERRRDFLQMVLDAQHSMNSVGVEGFDMVPESLSSSECTKEPPQRCHPTSTSKPFTV 328
            .||:::  ..||.||:.::||.:...|..|:                                |:
  Fly   254 ELRERE--NIRRNDFMDLLLDLRRQENGKGL--------------------------------TM 284

Mouse   329 DEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLFMGKHPAPEYHSLQEGLPYL 393
            :::..|||:|.:||.|..::.:|:..:.||.:.|.|::|..|::..:|||....|.::.| :|||
  Fly   285 EQMAAQAFVFFVAGFETSSSNMSYALFELAKNQDVQQKLRMEINDSIGKHGKLTYEAMME-MPYL 348

Mouse   394 DMVISETLRMYPPAFRFTREAAQDCEVLGQRIPA-----------GTVLEIAVGALHHDPEHWPN 447
            |..|:||||.||.....||.|::|.|     ||:           ||.:.|.|.|:|:|||.:|.
  Fly   349 DQTITETLRKYPALSSLTRLASEDYE-----IPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVYPE 408

Mouse   448 PETFDPERFTAEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFEASPETQVPL 512
            |..|.||||..:|..:|.|..:|.||.|||:|:|:|.|.:.||:.::.:|.:|||...|.:...|
  Fly   409 PHEFRPERFAPDACRERHPTAFLGFGDGPRNCIGLRFGRMQVKVGLITLLRRFRFSLPPGSPTQL 473

Mouse   513 QLESKS-ALGPKNGVYIKI 530
            ::..:: .|.|.:||.:::
  Fly   474 KVTKRNLILLPSDGVRLQV 492

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tbxas1NP_035669.3 p450 47..528 CDD:365848 150/505 (30%)
Cyp6a16NP_001285631.1 p450 32..492 CDD:278495 150/509 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D264519at33208
OrthoFinder 1 1.000 - - FOG0000037
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100014
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X40
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
65.820

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