Protein Alignment Tbx6 and bi

DIOPT Version :9

• Sequence 1: NP_035668.2
• Gene: Tbx6 / 21389
• MGIID: 102539
• Length: 436
• Species: Mus musculus
• Sequence 2: NP_001259238.1
• Gene: bi / 31379
• FlyBaseID: FBgn0000179
• Length: 1023
• Species: Drosophila melanogaster
• Alignment Length: 587
• Identity: 180/587 - (30%)
• Similarity: 240/587 - (40%)
• Gaps: 190/587 - (32%)

Mouse     3 HPRELYPSLGTGYRLGHPQPGADSTFPPALTEGYRYPDLDTSKLDCFLSGIEAAPHTL-AAAAPL 66
            || .|||  |.|.|.....|||   .|.|...|..|    |:..|..|:  .|..|.| .|..||
  Fly   262 HP-GLYP--GGGLRFPPHHPGA---HPHAHHLGSAY----TTAEDVVLA--SAVAHQLHPAMRPL 314

Mouse    67 PLLPSALGPETAPPPPEALHSLPGV----SLSLENQELWKEFSAVGTEMIITKAGRRMFPACRVS 127
                .||.||.           .||    .::||.::||::|..:||||:|||:||:|||..:..
  Fly   315 ----RALQPED-----------DGVVDDPKVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFR 364

Mouse   128 VTGLDPEARYLFLLDVVPVDGARYRWQGQHWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSF 192
            |:|||.:|:|:.|||:|..|..||::....|..:|||:|.:|.|:|||||||.||..||::.|||
  Fly   365 VSGLDAKAKYILLLDIVAADDYRYKFHNSRWMVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSF 429

Mouse   193 HRVKLTNSTLDPHGHL---ILHSMHKYQPRIHLVRATQLCSQHWGGVASFRFPETTFISVTAYQN 254
            |::||||:..|.||.:   ||:||||||||.|||||..:....:....::.|.||.||:||||||
  Fly   430 HKLKLTNNISDKHGFVSTTILNSMHKYQPRFHLVRANDILKLPYSTFRTYVFKETEFIAVTAYQN 494

Mouse   255 PRITQLKIAANPFAKGFRENGRNCKRERDARVKRK------------------------------ 289
            .:||||||..||||||||:.|...:.::.|.:..:
  Fly   495 EKITQLKIDNNPFAKGFRDTGAGKREKKQALMSNRGSDSDKLNPTHVSSSRAPLHLGHAGRPPHL 559

Mouse   290 -------------------LRGP---------------------------------------EPV 296
                               :.||                                       |..
  Fly   560 HPHAALLDNQQDDDDKLLDVVGPPQSPLLPLSHSLQQMHAHQHSAALAAWFNHLAGAGAGASEHA 624

Mouse   297 ATEACGSG-----------------DTPGGPCDSTLGGDIRDS-DPEQAPTPQEAASASAP---- 339
            |..|..:.                 |.....|..::||....: .|....:|:||..|:|.
  Fly   625 AAAAANASAEDALRRRLQADADVERDGSDSSCSESVGGSTGGAFRPTSTGSPKEAVGAAAAAAAA 689

Mouse   340 ---PCGG--PSAEAYL---LHPAAF-------HG--APSHL-----PARTPSFAEAP-DPGRPAP 381
               |.||  ||....:   :||:..       ||  .|.||     ||...:.:.|. :||....
  Fly   690 GLNPGGGSYPSPNISVGPPIHPSPHLLPYLYPHGLYPPPHLGLLHNPAAAAAMSPAGLNPGLLFN 754

Mouse   382 YSAAFLDLQPGPGGSAYQAAPSVP----------SFAPHFIQ---GGPFPLPYPG---------P 424
            ...|.....|...|.||.||...|          .|:|:.:.   |..|....||         |
  Fly   755 AQLALAAQHPALFGHAYAAAGHTPVSPLQGLKSHRFSPYSLPGSLGSAFDAVTPGSNANRSGDPP 819

Mouse   425 GG 426
            ||
  Fly   820 GG 821

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbx6	NP_035668.2	TBOX	90..277	CDD:238106	102/193 (53%)
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988	25/71 (35%)
		T-box	330..513	CDD:279278	98/182 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810