Protein Alignment Tbx5 and bi

DIOPT Version :9

• Sequence 1: XP_006530342.1
• Gene: Tbx5 / 21388
• MGIID: 102541
• Length: 537
• Species: Mus musculus
• Sequence 2: NP_001259238.1
• Gene: bi / 31379
• FlyBaseID: FBgn0000179
• Length: 1023
• Species: Drosophila melanogaster
• Alignment Length: 543
• Identity: 181/543 - (33%)
• Similarity: 240/543 - (44%)
• Gaps: 140/543 - (25%)

Mouse     1 MHPPVQSENLARAQEPLRTMADTDEGFGLARTPLEPDSKDRSCDSKPESALGAPSKSPSSPQAAF 65
            :||         |..|||.:...|:|.
  Fly   307 LHP---------AMRPLRALQPEDDGV-------------------------------------- 324

Mouse    66 TQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADD 130
                ::..||.|..::||.|||::||||:|||:||:|||..|.:|:||:.|.|||||:|||.|||
  Fly   325 ----VDDPKVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADD 385

Mouse   131 HRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHI---IL 192
            :||||.:::|.|.|||:|.||.|:|:|||||.||..||:::|||.|||||||..|..|.:   ||
  Fly   386 YRYKFHNSRWMVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTIL 450

Mouse   193 NSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGF-- 255
            |||||||||.|:|:|  |:......:.|.|:||.||.|||||:|||.|||||||:||||||||
  Fly   451 NSMHKYQPRFHLVRA--NDILKLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRD 513

Mouse   256 ---------------RGSDDLELHRMSRMQSKEYPVVPRSTVRHKVTSNHSPFSSETRALSTSSN 305
                           ||||..:|: .:.:.|...|:       |...:...|......||
  Fly   514 TGAGKREKKQALMSNRGSDSDKLN-PTHVSSSRAPL-------HLGHAGRPPHLHPHAAL----- 565

Mouse   306 LGSQYQCEN---GVSGPSQDLLPPPNPYPLAQEHSQIYHC------TKRKDEECSSTEHPYKKPY 361
            |.:|...::   .|.||.|..|.|.: :.|.|.|:..:..      .........::||   ...
  Fly   566 LDNQQDDDDKLLDVVGPPQSPLLPLS-HSLQQMHAHQHSAALAAWFNHLAGAGAGASEH---AAA 626

Mouse   362 METSPSEEDTF----------YRSGYPQQQGLSTSYRTESAQRQACMYASSAPPSEPV-PSLEDI 415
            ...:.|.||..          .|.|.......|....|..|.|.    .|:..|.|.| .:....
  Fly   627 AAANASAEDALRRRLQADADVERDGSDSSCSESVGGSTGGAFRP----TSTGSPKEAVGAAAAAA 687

Mouse   416 SCNTWPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSV 480
            :....|...||.|..::...|:      |.|.|     |:|.|.....:..|.||         :
  Fly   688 AAGLNPGGGSYPSPNISVGPPI------HPSPH-----LLPYLYPHGLYPPPHLG---------L 732

Mouse   481 AHQPVVRQCGPQTGLQSPGGLQP 503
            .|.|..      ....||.||.|
  Fly   733 LHNPAA------AAAMSPAGLNP 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbx5	XP_006530342.1	TBOX	72..260	CDD:238106	118/207 (57%)
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988	6/19 (32%)
		T-box	330..513	CDD:279278	114/184 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810