Protein Alignment Tbx4 and H15

DIOPT Version :9

• Sequence 1: NP_035666.2
• Gene: Tbx4 / 21387
• MGIID: 102556
• Length: 552
• Species: Mus musculus
• Sequence 2: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Alignment Length: 549
• Identity: 162/549 - (29%)
• Similarity: 239/549 - (43%)
• Gaps: 174/549 - (31%)

Mouse    24 ASNTSTTNAPEPALATPGLSGAALSS---------PPGQGAD----VAAAAAAAAEQT------- 68
            :||:..:|....:.:..|.|.||:.:         ||.|..:    ::...:.|.:.|
  Fly   205 SSNSGNSNTNSKSSSQRGRSAAAVGAAATPSPPPPPPSQSPEELERLSPEESPAQQPTPKIVGSC 269

Mouse    69 ----IENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTG----MNPKTKYILLIDIV 125
                :..::..|..||||.||||.||||||||:||||||:.:|..:|    :.|..:|.:|:|:|
  Fly   270 NCDDLTPVQCHLETKELWDKFHELGTEMIITKSGRRMFPTVRVSFSGPLRQIQPADRYAVLLDVV 334

Mouse   126 PADDHRYKFCDNK--WMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 188
            |.|..||::..::  |:|||||:|..|.|:|.|||.|.:.....:|:|||:|:|||||.:|..|.
  Fly   335 PLDSRRYRYAYHRSSWLVAGKADPPPPSRIYAHPDCPLSPEALRKQVVSFEKVKLTNNEMDKSGQ 399

Mouse   189 IILNSMHKYQPRLHIVKADENNAF-GS----KNTAFCTHVFPETSFISVTSYQNHKITQLKIENN 248
            ::|||||:||||:|:|:.....:. ||    ::....|.|||||.|.:||:|||..||:|||::|
  Fly   400 VVLNSMHRYQPRIHLVRLSHGQSIPGSPKELQDMDHKTFVFPETVFTAVTAYQNQLITKLKIDSN 464

Mouse   249 PFAKGFRGSD---------------DSDLRVARLQSKEYPVISKSIMRQRLVSSQLSAKPDVSPL 298
            |||||||.|.               |..:|.|.|:....|::|:       ::.|.:....::.|
  Fly   465 PFAKGFRDSSRLSDFDRDPMDAFFFDQHMRTAPLRFFPDPLMSQ-------LTPQEADAASMALL 522

Mouse   299 HSAHQALQHYQYENGAHMQFAAAEPQD---LPLNTFPTQRDSSLFYHCLKRRDSARHLDLPCKRS 360
            ..|.|           |:|.....|..   ||                        ||   .:||
  Fly   523 EKARQ-----------HLQMFGRSPYTEMLLP------------------------HL---YQRS 549

Mouse   361 YLETPSSVGDDHYFRSPPP-----------YDQQ--MLSPSYCSEVTPREACMYSSSGPEIAGVS 412
            ....|           |||           :.||  .|:..:.:....:.|...:::|
  Fly   550 AAPPP-----------PPPAPHLSAFQLGMWQQQWPQLTAGFLASANQQAALALAAAG------- 596

Mouse   413 AVDDLPPPPLSCNMWTSVSPYTSYSVQTMETVPYQPFPAHFTATTVMPRLPTIAAQSAQPPGNA- 476
             .:..|||.:      :|:|                 ||        |..||.:..||.|...|
  Fly   597 -ANRTPPPSM------AVAP-----------------PA--------PATPTSSCGSASPDLRAR 629

Mouse   477 --------HFSVYNQLSQSQVRERGPSAS 497
                    .||.| |:.|.|.   .|.||
  Fly   630 PQLNHYPQRFSPY-QVPQHQA---SPPAS 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbx4	NP_035666.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		7/34 (21%)
		TBOX	71..260	CDD:238106	99/214 (46%)
H15	NP_608926.2	TBOX	276..475	CDD:238106	99/198 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831484
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740