Protein Alignment Tbx1 and Doc1

DIOPT Version :9

• Sequence 1: NP_001360867.1
• Gene: Tbx1 / 21380
• MGIID: 98493
• Length: 529
• Species: Mus musculus
• Sequence 2: NP_648283.1
• Gene: Doc1 / 39039
• FlyBaseID: FBgn0028789
• Length: 391
• Species: Drosophila melanogaster
• Alignment Length: 361
• Identity: 140/361 - (38%)
• Similarity: 191/361 - (52%)
• Gaps: 70/361 - (19%)

Mouse   144 PKVASVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKR 208
            |.:..|..:||...||.:|:::|||||:||:||||||:.:|.|.|::..|.|.:|::.||:.|.|
  Fly    54 PTLPGVEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCR 118

Mouse   209 YRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSM 273
            |:  |..|.|:.||.|:|.:|.|::.||||||.||.|..|.:.|:|:|||||.||.:|||:|.||
  Fly   119 YK--FSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTNNTLDSSGHIVLASM 181

Mouse   274 HRYQPRFHVVYVDPRKDSE----KYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGF 334
            |:||||.|::     :.||    .:|.:  :.|||.||.|.|||||||.|||:|||.:|||||||
  Fly   182 HKYQPRLHII-----RSSELTQLPWAPQ--QAFVFPETEFVAVTAYQNDRITKLKIDNNPFAKGF 239

Mouse   335 RDCDPEDWPRNHRPGALPLVSAFARSRNPVASPT---QPNGSDKDAAEA------RREFDRDS-- 388
            |:...               |...|..|...:.|   :.:||...:.::      |::|::||
  Fly   240 RESGQ---------------SRCKRKLNSSGNSTLESEDDGSSVSSCDSPQAKRQRQDFEQDSTG 289

Mouse   389 --GPAALGDATHPPQLLARVLSPALP-----GPGGLVPLP--------GGSGGRHSPPHADLRLE 438
              .||..| ||||   :|..:||.|.     ||.|...||        ||     .||..   |.
  Fly   290 SVSPAYYG-ATHP---VANPMSPYLRHHLSYGPSGAAGLPPSIAAAYFGG-----VPPQI---LP 342

Mouse   439 APGASEPLHHHPYKYPAAAYDHYLGAKSRPAPYPLP 474
            .|    |..:.|...|.:.........|.|...|.|
  Fly   343 MP----PATYAPTVAPVSPVASQPVGSSTPTTSPRP 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbx1	NP_001360867.1	T-box	151..336	CDD:366363	98/188 (52%)
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	100/210 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2837
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940