Protein Alignment Tbx1 and H15

DIOPT Version :9

• Sequence 1: NP_001360867.1
• Gene: Tbx1 / 21380
• MGIID: 98493
• Length: 529
• Species: Mus musculus
• Sequence 2: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Alignment Length: 585
• Identity: 186/585 - (31%)
• Similarity: 254/585 - (43%)
• Gaps: 141/585 - (24%)

Mouse     2 DARSPLSARASAFSIASLVAAEA----SEGTAHRGPRPSDRAKLRRLPGSPAGMHFSTVTRDMEA 62
            |:..| ||.|:|.:.|:..||.|    ::..|.:..|.:.:.:.::........|.:|..:....
  Fly   130 DSEMP-SATAAAAAAATTAAAAAAALQAQQQARQALRVAQQQQQQQQQQRQQTHHHATTGKQQRQ 193

Mouse    63 FAASSLSGLGSPSPGADPFGPREPPPPRYDPCAAVPGA--PGPPPPRAYPFAPAPGAAGSSAAES 125
            ......|...:.|...:.....:....|....|||..|  |.||||        |.:......|.
  Fly   194 HHNHHSSNTNNSSNSGNSNTNSKSSSQRGRSAAAVGAAATPSPPPP--------PPSQSPEELER 250

Mouse   126 EGPGASRAAAVKAPVKKNPKVAS---------VSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPT 181
            ..|..|.|.      :..||:..         |...||.|.|||:|::||||||:||:|||||||
  Fly   251 LSPEESPAQ------QPTPKIVGSCNCDDLTPVQCHLETKELWDKFHELGTEMIITKSGRRMFPT 309

Mouse   182 FQVKLFG----MDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKG 242
            .:|...|    :.|...|.:|:|.||:|.:|||||:|.|||||||||||..|.|::.|||.|...
  Fly   310 VRVSFSGPLRQIQPADRYAVLLDVVPLDSRRYRYAYHRSSWLVAGKADPPPPSRIYAHPDCPLSP 374

Mouse   243 AQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVD-----PRKDSEKYAEENFKTF 302
            ....||:|||:|:|||||.:|.:|.::||||||||||.|:|.:.     |....| ..:.:.|||
  Fly   375 EALRKQVVSFEKVKLTNNEMDKSGQVVLNSMHRYQPRIHLVRLSHGQSIPGSPKE-LQDMDHKTF 438

Mouse   303 VFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDC--------DPED---WPRNHRPGAL----- 351
            ||.||.|||||||||..||:|||.||||||||||.        ||.|   :.::.|...|
  Fly   439 VFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLSDFDRDPMDAFFFDQHMRTAPLRFFPD 503

Mouse   352 PLVSAFARSRNPVASPTQPNGSDKDAAEARRE------------------FDRDSGPAALGDATH 398
            ||:|..        :|.:.:.:.....|..|:                  :.|.:.|.....|.|
  Fly   504 PLMSQL--------TPQEADAASMALLEKARQHLQMFGRSPYTEMLLPHLYQRSAAPPPPPPAPH 560

Mouse   399 P------------PQLLARVLSPALPGPGGLVPLPGGSGGRHSPPHADLRLEAP-------GASE 444
            .            |||.|..|:.|  .....:.|......|..||...:...||       |::.
  Fly   561 LSAFQLGMWQQQWPQLTAGFLASA--NQQAALALAAAGANRTPPPSMAVAPPAPATPTSSCGSAS 623

Mouse   445 P-------LHHHPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHAHPHHHHHPAVNPA 502
            |       |:|:|.::               :||.:|                .|....||.|.|
  Fly   624 PDLRARPQLNHYPQRF---------------SPYQVP----------------QHQASPPASNRA 657

Mouse   503  502
              Fly   658  657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbx1	NP_001360867.1	T-box	151..336	CDD:366363	110/193 (57%)
H15	NP_608926.2	TBOX	276..475	CDD:238106	113/199 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831480
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740