Protein Alignment EYA1 and eya1

DIOPT Version :10

• Sequence 1: NP_001357262.1
• Gene: EYA1 / 2138
• HGNCID: 3519
• Length: 621
• Species: Homo sapiens
• Sequence 2: XP_017950627.1
• Gene: eya1 / 779594
• XenbaseID: XB-GENE-479279
• Length: 605
• Species: Xenopus tropicalis
• Alignment Length: 563
• Identity: 516/563 - (91%)
• Similarity: 537/563 - (95%)
• Gaps: 3/563 - (0%)

Human    61 SNSMTPNGTEV-KTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYP 124
            |..:..:.|:: ||||||||:..:|||||.|:|||||.||||.:|||...||| ||||||||.||
 Frog    44 SGGLVTDRTDIFKTEPMSSSDIVTTTADGHLDNFSGSVIGSSGYSPRQAQQFS-PQIYPSNRAYP 107

Human   125 HILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQ 189
            ||||.||||||||||||||::||||||||||||||||||||..||||||||||||||.|.|||||
 Frog   108 HILPNPSSQTMAAYGQTQFSSGMQQATAYATYPQPGQPYGIPPYGALWAGIKTEGGLPQPQSPGQ 172

Human   190 TGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQ 254
            |||||||:|||||||||||||||||||||||:||||.|:||||||:|||||||:|||||||||||
 Frog   173 TGFLSYGSSFSTPQPGQAPYSYQMQGSSFTTASGIYAGSNSLTNSTGFNSSQQEYPSYPSFGQGQ 237

Human   255 YAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTD-PTAEYSTIHSPSTPIKD 318
            |||||||||||:|||||||||||||||.||||||||||||||||||| .||||||||||||||||
 Frog   238 YAQYYNSSPYPSHYMTSSNTSPTTPSTTATYQLQEPPSGITSQAVTDHSTAEYSTIHSPSTPIKD 302

Human   319 SDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPT 383
            ||||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   303 SDSDRLRRSSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPT 367

Human   384 SVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLC 448
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   368 SVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLC 432

Human   449 LATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALK 513
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   433 LATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALK 497

Human   514 ALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKV 578
            ||:|||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   498 ALTLIHSRSNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKV 562

Human   579 VYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 621
            ||||:|||||||||||||:||||||:|||||||||||||||||
 Frog   563 VYVVVGDGVEEEQGAKKHSMPFWRITSHSDLMALHHALELEYL 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EYA1	NP_001357262.1	Chi1	126..>304	CDD:442692	161/178 (90%)
		HAD_Eya	350..621	CDD:319789	265/270 (98%)
eya1	XP_017950627.1	HAD_Eya	334..605	CDD:319789	265/270 (98%)