Protein Alignment EYA1 and eya1

DIOPT Version :10

• Sequence 1: NP_001357262.1
• Gene: EYA1 / 2138
• HGNCID: 3519
• Length: 621
• Species: Homo sapiens
• Sequence 2: XP_073796093.1
• Gene: eya1 / 30436
• ZFINID: ZDB-GENE-990712-18
• Length: 630
• Species: Danio rerio
• Alignment Length: 595
• Identity: 530/595 - (89%)
• Similarity: 565/595 - (94%)
• Gaps: 2/595 - (0%)

Human    28 RSMEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNN 92
            ||||||||.|||||:|||||||:||.:.|||||:|||||||||||||||||||.|::.|||||::
Zfish    37 RSMEMQDLASPHSRVSGSSESPNGPNIDNSHINNNSMTPNGTEVKTEPMSSSEIATSVADGSLDS 101

Human    93 FSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYP 157
            |||||||:|.||||.||||| ||||||||||||||||||:|.||||||||:|||||||.||.|||
Zfish   102 FSGSAIGTSGFSPRQTHQFS-PQIYPSNRPYPHILPTPSAQNMAAYGQTQYTTGMQQAAAYGTYP 165

Human   158 QPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSS 222
            |||||||||:||.|||||||||||:|:|||||:|||||.:||||||.|||||||||||.||||:|
Zfish   166 QPGQPYGISAYGPLWAGIKTEGGLTQAQSPGQSGFLSYSSSFSTPQTGQAPYSYQMQGGSFTTTS 230

Human   223 GIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQL 287
            |:|.|:||||||:||||:||||||||:|||.|||||||||||.:.||||:|||||||||.|||.|
Zfish   231 GLYAGSNSLTNSTGFNSTQQDYPSYPTFGQSQYAQYYNSSPYTSPYMTSNNTSPTTPSTTATYTL 295

Human   288 QEPPSGITSQAVTD-PTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLE 351
            |||||||||||:|: ||.||||||||||||||||||||||.||.|:|||||||||||||||||||
Zfish   296 QEPPSGITSQALTEQPTGEYSTIHSPSTPIKDSDSDRLRRASDVKARGRGRRNNNPSPPPDSDLE 360

Human   352 RVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHI 416
            |||||||||||||||||||||||||:|||||||||||||||||||||||||.|||||||||||||
Zfish   361 RVFIWDLDETIIVFHSLLTGSYANRFGRDPPTSVSLGLRMEEMIFNLADTHFFFNDLEECDQVHI 425

Human   417 DDVSSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNV 481
            |||||||||||||||||.||||.|||||||||||||||||||||||||||||||||||.||||||
Zfish   426 DDVSSDDNGQDLSTYNFSTDGFHAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYTTYKNNV 490

Human   482 GGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGL 546
            ||||||||||||||||||||||||||||||||||:|||||:||||||||||||||||||||||||
Zfish   491 GGLLGPAKREAWLQLRAEIEALTDSWLTLALKALTLIHSRSNCVNILVTTTQLIPALAKVLLYGL 555

Human   547 GIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMA 611
            |:|||||||||||||||||||||:||||||||||||:|||||||||:|||.||||||||||||||
Zfish   556 GVVFPIENIYSATKIGKESCFERVIQRFGRKVVYVVVGDGVEEEQGSKKHNMPFWRISSHSDLMA 620

Human   612 LHHALELEYL 621
            |||||:||||
Zfish   621 LHHALDLEYL 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EYA1	NP_001357262.1	Chi1	126..>304	CDD:442692	147/178 (83%)
		HAD_Eya	350..621	CDD:319789	257/270 (95%)
eya1	XP_073796093.1	None