DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tal1 and HLH4C

DIOPT Version :9

Sequence 1:	XP_006502972.1	Gene:	Tal1 / 21349	MGIID:	98480	Length:	335	Species:	Mus musculus
Sequence 2:	NP_001259243.1	Gene:	HLH4C / 31397	FlyBaseID:	FBgn0011277	Length:	191	Species:	Drosophila melanogaster

Alignment Length:	161	Identity:	49/161 - (30%)
Similarity:	67/161 - (41%)	Gaps:	51/161 - (31%)

- Green bases have known domain annotations that are detailed below.

Mouse    89 EARLRVPTTELCRPPGPAPAPAPASAPAELPGDGRMVQLSPPALAAPAGPGRALLYSLSQPLASL 153
            :||:   ..|....|.|.|.|.||                         |.|.     :.|:|.|
  Fly    55 QARM---ACETAAQPAPPPPPTPA-------------------------PRRR-----TTPIAHL 86

Mouse   154 GSGFFGEPDAFPMFTNNNRVKRRPSPYEMEISDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRK 218
                  :|......:...|.:||.:..:...:..            :|||.|.:..|.:||||||
  Fly    87 ------DPSELVGLSREERRRRRRATLKYRTAHA------------TRERIRVEAFNVSFAELRK 133

Mouse   219 LIPTHPPDKKLSKNEILRLAMKYINFLAKLL 249
            |:||.||||||||.|||:||:.||.:|..:|
  Fly   134 LLPTLPPDKKLSKIEILKLAICYIAYLNHVL 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tal1	XP_006502972.1	bHLH_TS_TAL1	191..255	CDD:381549	31/59 (53%)
HLH4C	NP_001259243.1	HLH	108..165	CDD:238036	31/69 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810