Protein Alignment EWSR1 and GAR1

DIOPT Version :9

• Sequence 1: XP_011528297.1
• Gene: EWSR1 / 2130
• HGNCID: 3508
• Length: 670
• Species: Homo sapiens
• Sequence 2: NP_011957.1
• Gene: GAR1 / 856489
• SGDID: S000001131
• Length: 205
• Species: Saccharomyces cerevisiae
• Alignment Length: 331
• Identity: 90/331 - (27%)
• Similarity: 106/331 - (32%)
• Gaps: 153/331 - (46%)

Human   310 RGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVT 374
            ||| :||||||.|||.     |||.........:||         ||                 |
Yeast     4 RGG-NRGGRGGFRGGF-----RGGRTGSARSFQQGP---------PD-----------------T 36

Human   375 LDDLADFFKQC--GVVKMNKRTGQPMIH--IYLDKETGKPKGDA----------TVSYEDPPTAK 425
            :.::..|...|  .:|..:..|..|..:  |||:.:|...|.|.          |:...|...|.
Yeast    37 VLEMGAFLHPCEGDIVCRSINTKIPYFNAPIYLENKTQVGKVDEILGPLNEVFFTIKCGDGVQAT 101

Human   426 AAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGP-------GGPGG 483
            :..|        |.|..:: |.|..|:.           |.:|.|...||..|       |.|||
Yeast   102 SFKE--------GDKFYIA-ADKLLPIE-----------RFLPKPKVVGPPKPKNKKKRSGAPGG 146

Human   484 PMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPSIGDFCCDVIVCRGCGNQNF 548
            ..|...||||.||||     ||.||..|
Yeast   147 RGGASMGRGGSRGGF-----RGGRGGSS------------------------------------- 169

Human   549 AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGP-GGMFRGG-RGGDRG 611
                                                .||||||...|||. ||.|||| |||.||
Yeast   170 ------------------------------------FRGGRGGSSFRGGSRGGSFRGGSRGGSRG 198

Human   612 GFRGGR 617
            ||||||
Yeast   199 GFRGGR 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EWSR1	XP_011528297.1	RRM	<351..>459	CDD:223796	23/121 (19%)
		RRM_EWS	362..445	CDD:240977	18/96 (19%)
		zf-RanBP	519..561	CDD:279035	0/41 (0%)
		RanBP2-type Zn finger	523..557	CDD:275375	0/33 (0%)
GAR1	NP_011957.1	Gar1	29..>124	CDD:398216	26/140 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000