Protein Alignment EWSR1 and SPBC660.06

DIOPT Version :9

• Sequence 1: XP_011528297.1
• Gene: EWSR1 / 2130
• HGNCID: 3508
• Length: 670
• Species: Homo sapiens
• Sequence 2: NP_595085.1
• Gene: SPBC660.06 / 2541137
• PomBaseID: SPBC660.06
• Length: 273
• Species: Schizosaccharomyces pombe
• Alignment Length: 328
• Identity: 90/328 - (27%)
• Similarity: 100/328 - (30%)
• Gaps: 105/328 - (32%)

Human   340 PMDEGP--DLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIY 402
            |..|.|  :|.|.||  |...|.|:|:|....|.|....:.|  :........|..|........
pombe    37 PQWEPPVENLKLAPP--PGATSVNTAVYNNNNNTSAANTNAA--YNANTAANANANTATTTNAAA 97

Human   403 LDKETGKPKGDATVSYEDPPTAKAAVEW-FDGKD---FQGSKLKVSLARKKPPMNSMRGGLPPRE 463
            .......|...|..:....|.|.|.... .||.|   |.|.              :...|.....
pombe    98 TTSAAYNPNAPANTNAAYYPNAAATTTTNADGSDKGLFSGL--------------TSSNGYTTGN 148

Human   464 GRGMP---PPLRGGPGGPGGPGGPMGRMGG----RGGDRGGFPPRGPRGSRGNPSGGGNVQHRAG 521
            ....|   .|:..|.||....|.....:|.    ||.:.|||      |..|..|||
pombe   149 SYSRPSYVAPVAAGLGGLALGGLASHALGNLFHHRGHNGGGF------GGFGGGSGG-------- 199

Human   522 DWQCPNPSIGDFCCDVIVCRGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMR 586
                                                ..|.|.||        ||..|.||.|...
pombe   200 ------------------------------------PPPGPGGF--------GGFGGFGGEGHHH 220

Human   587 GGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRG 651
            ||.||.  .||||| |.||.||..||        .||||||..|..|||.|     .||..||.|
pombe   221 GGHGGF--GGGPGG-FEGGPGGFGGG--------PGGFGGGLGGFGGGPGG-----FGGGPGGHG 269

Human   652 GPG 654
            |||
pombe   270 GPG 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EWSR1	XP_011528297.1	RRM	<351..>459	CDD:223796	22/111 (20%)
		RRM_EWS	362..445	CDD:240977	17/86 (20%)
		zf-RanBP	519..561	CDD:279035	0/41 (0%)
		RanBP2-type Zn finger	523..557	CDD:275375	0/33 (0%)
SPBC660.06	NP_595085.1	WW	9..44	CDD:197736	3/6 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000