Protein Alignment EWSR1 and gar1

DIOPT Version :9

• Sequence 1: XP_011528297.1
• Gene: EWSR1 / 2130
• HGNCID: 3508
• Length: 670
• Species: Homo sapiens
• Sequence 2: NP_596365.1
• Gene: gar1 / 2540705
• PomBaseID: SPBC20F10.01
• Length: 194
• Species: Schizosaccharomyces pombe
• Alignment Length: 333
• Identity: 86/333 - (25%)
• Similarity: 110/333 - (33%)
• Gaps: 163/333 - (48%)

Human   315 RGGRGGG-RGGMGSAGERGGFN--KPGGPMDEGPDLDL------GPPVDPDEDSD----NSAIYV 366
            ||||||| |||      |||..  .|.||.|:..:|.|      |..|....:..    |:.||:
pombe     4 RGGRGGGFRGG------RGGSRPFTPSGPPDQVIELGLFMHDCEGEMVCQSTNVKIPYFNAPIYL 62

Human   367 QGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP-KGDATVSYEDPPTAKAAVEW 430
            :..:....:|::..                ||..:|.   |.|| :|..:.|::
pombe    63 ENKSQIGKIDEVFG----------------PMNQVYF---TVKPSEGIVSSSFK----------- 97

Human   431 FDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDR 495
                  .|.|:.:| ..|..|::           |.:|.|...|
pombe    98 ------VGDKVYLS-GDKLIPLD-----------RFLPKPKTVG--------------------- 123

Human   496 GGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPSIGDFCCDVIVCRGCGNQNFAWRTECNQCKAP 560
                |:.|:|:|..|:
pombe   124 ----PKKPKGARNGPA------------------------------------------------- 135

Human   561 KPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG-RGGDRGGFRGG-RGMDRGG 623
                             ||||.||.||||||  .|||.||..||| .||.||||.|| ||..|||
pombe   136 -----------------GRGGRGGFRGGRGG--SRGGFGGNSRGGFGGGSRGGFGGGSRGGSRGG 181

Human   624 FGGGRRGG 631
            |.||.|||
pombe   182 FRGGSRGG 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EWSR1	XP_011528297.1	RRM	<351..>459	CDD:223796	18/112 (16%)
		RRM_EWS	362..445	CDD:240977	13/83 (16%)
		zf-RanBP	519..561	CDD:279035	0/41 (0%)
		RanBP2-type Zn finger	523..557	CDD:275375	0/33 (0%)
gar1	NP_596365.1	Gar1	20..>128	CDD:282290	30/180 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000