Protein Alignment ETV6 and Ets97D

DIOPT Version :10

• Sequence 1: NP_001978.1
• Gene: ETV6 / 2120
• HGNCID: 3495
• Length: 452
• Species: Homo sapiens
• Sequence 2: NP_001263000.1
• Gene: Ets97D / 43236
• FlyBaseID: FBgn0004510
• Length: 484
• Species: Drosophila melanogaster
• Alignment Length: 445
• Identity: 99/445 - (22%)
• Similarity: 164/445 - (36%)
• Gaps: 165/445 - (37%)

Human     1 MSETPAQCSIKQERI--SYTPPE-SPVPSYASSTPLHVPVPRALR--MEEDSIR----------- 49
            :..|.|..:...|.:  ..:||| :...|.:|.:|:..|:.|..:  .||:|:.
  Fly   120 LKPTEAALAALAEEVVGQLSPPETASQKSSSSESPIKTPLKRMHKEDSEEESVEGKDVKPVLNWV 184

Human    50 LPAHLRLQPI---------YWSRDDVAQWLKWAENEFSLRPIDSNTFEMNGKALLLLTKEDFRYR 105
            |.:..:.:.|         .|:...|..||:||..:|.|..|:.:.::|||:.|..:|.|:|..:
  Fly   185 LDSKFKREQIRLKIPEAANEWTHAHVTYWLEWAVKQFELVGINMSDWQMNGQELCAMTHEEFNQK 249

Human   106 SPHS-GDVLYELLQHILKQRKPRILFSPFFHPGNSIHTQPEVILHQNHEEDNCVQRTPRPSVDNV 169
            .|.. |::.:..|| :||:             .|.:.     ::|:..||    ||.|:
  Fly   250 LPRDPGNIFWTHLQ-LLKE-------------CNFVS-----VVHKRAEE----QRKPK------ 285

Human   170 HHNPPTIELLHRSRSPITTNHRPSPDPEQRPLRSPLDNMIRRLSPAERAQGPRPHQENNHQESYP 234
               .|.|    .|.:.|:||...|...|||.:|                            :||
  Fly   286 ---QPRI----MSANSISTNSGGSLSLEQRIMR----------------------------KSY- 314

Human   235 LSVSPMENNHCPASSESHPKPSSPRQESTRVIQLMPSPIMHPLILNPRHSVDFKQSRLSEDGLHR 299
                                                                  ||..|.|.:..
  Fly   315 ------------------------------------------------------QSVKSSDSVES 325

Human   300 EGKPINLSHREDLAYMNHIMVSVSPPEEHAMPIGRIADCRLLWDYVYQLLSDSRYENFIRWEDKE 364
            ....:|.|:...:...|:..|.                   ||.::.::|:|..:.:.|.|...|
  Fly   326 TTSSMNPSNYTTIGSGNNGQVQ-------------------LWQFLLEILTDCEHTDVIEWVGTE 371

Human   365 SKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIRKEPGQRLLFRF 419
            .: |::.||:.:|||||..||:..|.|||:|||||:||..::|.|..|:|..::|
  Fly   372 GE-FKLTDPDRVARLWGEKKNKPAMNYEKLSRALRYYYDGDMISKVSGKRFAYKF 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETV6	NP_001978.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		7/31 (23%)
		SAM_PNT-Tel_Yan	56..123	CDD:176085	22/76 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..262		16/103 (16%)
		ETS	338..424	CDD:197710	33/82 (40%)
Ets97D	NP_001263000.1	GABP-alpha	48..123	CDD:463311	0/2 (0%)
		SAM_PNT-GABP-alpha	184..272	CDD:176084	25/101 (25%)
		ETS	345..429	CDD:197710	34/101 (34%)