Protein Alignment ETV6 and Ets21C

DIOPT Version :10

• Sequence 1: NP_001978.1
• Gene: ETV6 / 2120
• HGNCID: 3495
• Length: 452
• Species: Homo sapiens
• Sequence 2: NP_523445.1
• Gene: Ets21C / 33229
• FlyBaseID: FBgn0005660
• Length: 475
• Species: Drosophila melanogaster
• Alignment Length: 408
• Identity: 88/408 - (21%)
• Similarity: 127/408 - (31%)
• Gaps: 192/408 - (47%)

Human    19 PPESPVPSYASSTPLHVPVPRALRMEEDSIR--LPAHLRLQPIYWSRDDVAQWLKWAENEFSLRP 81
            |..:|.|. |.|:|...|.||  |...||.|  .|..:.:.|..|:.:|:|.|::||..:|.|.|
  Fly   112 PLATPTPP-AVSSPHQAPSPR--RNSSDSNRSVSPVEVPVDPHAWTPEDIASWVRWATRKFKLDP 173

Human    82 -IDSNTFEMNGKALLLLTKEDFRY-RSPHSGDVLYELLQHILKQRKPRILFSPFFHPGNSIHTQP 144
             .|.:.|..:.:.|..|::.||.. .....|.:|  |.||.
  Fly   174 EPDIDRFPKDAQELCDLSRADFWVCAGSRRGGML--LAQHF------------------------ 212

Human   145 EVILHQNHEEDNCVQRTPRPSVDNVHHNPPTIELLH---RSRSPITTNHRPSPDPEQRPLRSPLD 206
                                          .|.|.|   |..||:..:..|:|
  Fly   213 ------------------------------AISLYHATGRETSPMLNDDEPNP------------ 235

Human   207 NMIRRLSPAERAQGPRPHQENNHQESYPLSVSPMENNHCPASSESHPKPSSPRQESTRVIQLMPS 271
                                      |.|           .::.||
  Fly   236 --------------------------YQL-----------LNAASH------------------- 244

Human   272 PIMHPLILNPRHSVDFKQSRLSEDGLHREGKPINLSHREDLAYMNHIMVSVSPPEEHAMPIGRIA 336
                               ||...|   .|..|.
  Fly   245 -------------------RLVAQG---SGGQIQ------------------------------- 256

Human   337 DCRLLWDYVYQLLSDSRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHY 401
                ||.::.:||:||...|.|.||.:..: ||::||:.:||.||..|.:.||.|:|:|||||:|
  Fly   257 ----LWQFLLELLADSSNANAISWEGQSGE-FRLIDPDEVARRWGERKAKPNMNYDKLSRALRYY 316

Human   402 YKLNIIRKEPGQRLLFRF 419
            |..||:.|..|:|..::|
  Fly   317 YDKNIMTKVHGKRYAYKF 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETV6	NP_001978.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		4/10 (40%)
		SAM_PNT-Tel_Yan	56..123	CDD:176085	21/68 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..262		12/106 (11%)
		ETS	338..424	CDD:197710	36/82 (44%)
Ets21C	NP_523445.1	SAM_PNT	149..217	CDD:188876	22/123 (18%)
		ETS	254..339	CDD:197710	37/117 (32%)