DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ETV5 and Ets97D

DIOPT Version :9

Sequence 1:	NP_004445.1	Gene:	ETV5 / 2119	HGNCID:	3494	Length:	510	Species:	Homo sapiens
Sequence 2:	NP_001263000.1	Gene:	Ets97D / 43236	FlyBaseID:	FBgn0004510	Length:	484	Species:	Drosophila melanogaster

Alignment Length:	107	Identity:	51/107 - (47%)
Similarity:	72/107 - (67%)	Gaps:	2/107 - (1%)

- Green bases have known domain annotations that are detailed below.

Human   366 GSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYY 430
            |.:||||||:.:|.|..:...|.|.|...||||.:|:.|||.||.:||:|||||:||||:|||||
  Fly   344 GQVQLWQFLLEILTDCEHTDVIEWVGTEGEFKLTDPDRVARLWGEKKNKPAMNYEKLSRALRYYY 408

Human   431 EKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESE 472
            :..::.||:|:|:.|||.||...|  :.:..|:...|.:|.:
  Fly   409 DGDMISKVSGKRFAYKFDCDLKLL--IGYDANELSTLVSEGK 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ETV5	NP_004445.1	ETS_PEA3_N	2..366	CDD:309665	51/107 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	131..208
		ETS	367..452	CDD:197710	46/84 (55%)
Ets97D	NP_001263000.1	GABP-alpha	48..123	CDD:288472
		SAM_PNT-GABP-alpha	184..272	CDD:176084
		ETS	345..429	CDD:197710	45/83 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.770