Protein Alignment ETV5 and etv1

DIOPT Version :10

• Sequence 1: NP_004445.1
• Gene: ETV5 / 2119
• HGNCID: 3494
• Length: 510
• Species: Homo sapiens
• Sequence 2: NP_989219.1
• Gene: etv1 / 394827
• XenbaseID: XB-GENE-489879
• Length: 495
• Species: Xenopus tropicalis
• Alignment Length: 537
• Identity: 318/537 - (59%)
• Similarity: 367/537 - (68%)
• Gaps: 69/537 - (12%)

Human     1 MDGFYDQQVPFMVPGKSRSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAEAQVPD 65
            ||||||||||:|||..........|....||||||:.||||||||||||||||||.|||||||||
 Frog     1 MDGFYDQQVPYMVPNNQSGGTSHERTSSSRKRKFLNRDLAHDSEELFQDLSQLQETWLAEAQVPD 65

Human    66 -------------------DEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSEL-SSCSHEQALGA 110
                               |||||||:|::||..|. .|.|||:|.||||||| ::||.||....
 Frog    66 NDEQFVPDYQAENSQVPDNDEQFVPDYQAENLAFHC-VPLKIKKEPHSPSSELNTACSQEQPFKF 129

Human   111 NYGEKCLYNYCAYDRKPPSGFKPLTPPT---TPLSPTHQNPLFPPPQATLPTSGHAPAAGPVQGV 172
            :||||||||..|||:||..|.:|..|||   ||:||.|                ||
 Frog   130 SYGEKCLYNVSAYDQKPQVGMRPSNPPTPASTPVSPLH----------------HA--------- 169

Human   173 GPAPAPHSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGVPG 237
              :|.|...|:|   .:.:    |||.|...|  :.:|.|..:.||:|||||||:.|||.|.:|.
 Frog   170 --SPNPAQTPKP---DRIY----PPHIPPSQP--ISDNSYSMDHRFRRQLSEPCNSFPPLPAMPR 223

Human   238 DNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPG-PPAHGFQSPMGIKQEPRDYCV 301
            :.||.|.||||||.:..   ||||||||||||:|||.  .|.| .|:..:..|:.|||||||:..
 Frog   224 EGRPMYQRQMSEPSIQF---PPQGFKQEYHDPVYEHN--NMVGNAPSQAYPPPLMIKQEPRDFAY 283

Human   302 DSEVPNCQSSYMRGGYF---SSSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGPPYQ 363
            |||||:|.|.|||...|   .:..||..|||.||.:|||||||||:.||.:||||.:|||||.||
 Frog   284 DSEVPSCHSIYMRQEAFLTHPNGTEGCMYEKGPRQFFDDTCVVPEKFEGDIKQEPGLYREGPTYQ 348

Human   364 RRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRY 428
            ||||||||||||.|||||||:||||||||||||||||||||||||||||||||||||||||||||
 Frog   349 RRGSLQLWQFLVALLDDPANSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRY 413

Human   429 YYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESECHLSEEDTLPLTHFEDSPAYL 493
            |||||||||||||||||||||||:|||||||||||||.||.:.|.|::||||:||:||:::..|:
 Frog   414 YYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDIERHVNEEDTVPLSHFDENMPYM 478

Human   494 LDMDRCSSLPYAEGFAY 510
            .|...|::.||.||:.|
 Frog   479 QDGGYCNTHPYNEGYVY 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETV5	NP_004445.1	ETS_PEA3_N	1..366	CDD:461371	200/391 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..208		20/79 (25%)
		ETS	367..452	CDD:197710	82/84 (98%)
etv1	NP_989219.1	ETS_PEA3_N	1..351	CDD:461371	200/391 (51%)
		ETS	352..436	CDD:197710	81/83 (98%)