Protein Alignment ETV5 and etv5a

DIOPT Version :10

• Sequence 1: NP_004445.1
• Gene: ETV5 / 2119
• HGNCID: 3494
• Length: 510
• Species: Homo sapiens
• Sequence 2: NP_001119933.1
• Gene: etv5a / 337626
• ZFINID: ZDB-GENE-030131-9572
• Length: 524
• Species: Danio rerio
• Alignment Length: 544
• Identity: 341/544 - (62%)
• Similarity: 389/544 - (71%)
• Gaps: 54/544 - (9%)

Human     1 MDGFYDQQVPFMVPGKSRS---EECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAEAQ 62
            ||||||||||||||...:|   ||...|||.|||||.::|:||.|:||||||||||||.|:||||
Zfish     1 MDGFYDQQVPFMVPPNQKSLQVEEPYNRPVNDRKRKLVETELAQDTEELFQDLSQLQEIWIAEAQ 65

Human    63 VPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSSCSHEQALGANYGEKCLYNYCAYDRKP 127
            |||||||||||||::|:.|.||..|||||| |||.|||.||.::: ...|||||||:|.||:|||
Zfish    66 VPDDEQFVPDFQSESLMFHGPPLAKIKREL-SPSKELSPCSQDRS-PMPYGEKCLYSYSAYERKP 128

Human   128 PSGFKPLTPPTTPLSP-THQNPLFPPP---QATLPTSGHAPAAGPVQG----VGPAP----APHS 180
            .:||||||||:||:|| ...|.|...|   |...|.|..|.....:.|    ....|    .||.
Zfish   129 STGFKPLTPPSTPVSPCVPSNALATRPLHEQTPPPVSNTALGQRLLHGQPTMTKSTPNQTCVPHH 193

Human   181 LPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPP---------QPGV- 235
            ...|     .|.||.||        :..|..:.:|.||||||||||.||||         .|.|
Zfish   194 SQSP-----PFVVPCPP--------LNRETHFSNEPRFQRQLSEPCLPFPPSDAQGRPSFMPQVA 245

Human   236 ---PGDNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLY-EHGVPGMPGPPAHGFQSPMGIKQEP 296
               |.|.||.||||||||:||.   ||||||||..||.| |.|||.| ||....|. ||.|||||
Zfish   246 CTSPRDGRPPYHRQMSEPLVPV---PPQGFKQELLDPRYVEQGVPNM-GPSQAAFH-PMAIKQEP 305

Human   297 RDYCVDSEVPNCQSSYMRGGYFSSSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGPP 361
            ||:|.|||||.||||:.|...|..:||.||::::.:|||||||||||||||||||||::||||||
Zfish   306 RDFCFDSEVPKCQSSFGRAASFYQNHENFSFDREQQLYFDDTCVVPERLEGKVKQEPSVYREGPP 370

Human   362 YQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSL 426
            ||||||||||||||||||||:|.||||||||||||||||||||||||||||||||||||||||||
Zfish   371 YQRRGSLQLWQFLVTLLDDPSNGHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSL 435

Human   427 RYYYEKGIMQ--KVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESE-CHLSEEDTLPLTHFED 488
            ||||||||||  |||||||||||||||:|||||||||||||.|||:.: ....::|||||.|::|
Zfish   436 RYYYEKGIMQKVKVAGERYVYKFVCDPEALFSMAFPDNQRPNLKADPDGLPTVDDDTLPLAHYDD 500

Human   489 SPAYLLD-MDRC-SSLPYAEGFAY 510
            ..:||:| .::| |.:|:.:|:.|
Zfish   501 GSSYLVDGGEQCVSGMPFPDGYVY 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETV5	NP_004445.1	ETS_PEA3_N	1..366	CDD:461371	225/393 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..208		28/88 (32%)
		ETS	367..452	CDD:197710	82/86 (95%)
etv5a	NP_001119933.1	ETS_PEA3_N	1..375	CDD:461371	225/393 (57%)
		ETS	376..462	CDD:197710	81/85 (95%)