DRSC/TRiP Functional Genomics Resources

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Protein Alignment ETV5 and etv4

DIOPT Version :10

Sequence 1:NP_004445.1 Gene:ETV5 / 2119 HGNCID:3494 Length:510 Species:Homo sapiens
Sequence 2:XP_012822986.1 Gene:etv4 / 100486339 XenbaseID:XB-GENE-6051133 Length:365 Species:Xenopus tropicalis


Alignment Length:440 Identity:182/440 - (41%)
Similarity:220/440 - (50%) Gaps:132/440 - (30%)


- Green bases have known domain annotations that are detailed below.


Human    61 AQVPD-DEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSSCSHEQALGANYGEKCLYNYCAYD 124
            ||||| ||||..|.||:|:..:: ||.|||:              ||....|...:||| ..|| 
 Frog    45 AQVPDSDEQFPQDMQSENITFYS-PPMKIKK--------------EQQYRYNSDGQCLY-ADAY- 92

Human   125 RKPPSGFKPLTPPTTPLSPTHQ--NPLFPPPQATLPTSGH---------APAAGPVQGVGPAPAP 178
                                ||  :.:..|.|.:..:..|         |...|.:|   .|||.
 Frog    93 --------------------HQTGHGIISPNQGSQKSQIHYFSTEGRRFAIQQGSIQ---YAPAE 134

Human   179 HSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGVPGDNRPSY 243
            ..|.|   .:..:|.|...:.|.|..::..|    :...:|.|:||||..:..|.          
 Frog   135 EYLTE---HKSRYAEPIDTYLPFQSLQLSRE----TSDGYQSQISEPCLQYLQQE---------- 182

Human   244 HRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPG-PPAHGFQSPMGIKQEPRDYCVDSEVPN 307
                              ||::||:||.|.  |...| ..|....|.:.||||..||..||    
 Frog   183 ------------------FKEKYHEPLSEE--PNHLGNHKAQQLPSNVVIKQEQADYSYDS---- 223

Human   308 CQSSYMRGGYFSSSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGPPYQRRGSLQLWQ 372
                                                  .|.:|||...||:.|||||||||||||
 Frog   224 --------------------------------------AGDIKQEAVPYRDRPPYQRRGSLQLWQ 250

Human   373 FLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQK 437
            |||.|||:|.|:||||||||||||||||||||||.||:|||||||||||||||||||||||||||
 Frog   251 FLVALLDNPTNSHFIAWTGRGMEFKLIEPEEVARLWGMQKNRPAMNYDKLSRSLRYYYEKGIMQK 315

Human   438 VAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESECHLSEEDTLPLTHFE 487
            ||||||||||||||:||||:||.|:|.|.||:||:|.:.||.|:||:|.:
 Frog   316 VAGERYVYKFVCDPEALFSLAFNDSQCPSLKSESDCRIHEEYTVPLSHLD 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ETV5NP_004445.1 ETS_PEA3_N 1..366 CDD:461371 81/317 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 131..208 17/87 (20%)
ETS 367..452 CDD:197710 78/84 (93%)
etv4XP_012822986.1 ETS_PEA3_N 45..244 CDD:461371 81/317 (26%)
ETS 245..329 CDD:197710 77/83 (93%)

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