DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ETV4 and pnt

DIOPT Version :9

Sequence 1:NP_001073143.1 Gene:ETV4 / 2118 HGNCID:3493 Length:484 Species:Homo sapiens
Sequence 2:NP_524461.2 Gene:pnt / 42757 FlyBaseID:FBgn0003118 Length:718 Species:Drosophila melanogaster


Alignment Length:292 Identity:99/292 - (33%)
Similarity:130/292 - (44%) Gaps:88/292 - (30%)


- Green bases have known domain annotations that are detailed below.


Human   165 SSGTSQPHPG--HGYLGEHSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQ 227
            |.|.|....|  :||           ||....|.....||......|..:.:    ||..|||: 
  Fly   509 SGGASGGSTGNSNGY-----------LDSSSEFYGSYAGRNRFHDGYPPEFT----PYDAQSFQ- 557

Human   228 EYHDPLYEQAGQP-AVDQ-GGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSP 290
                   ....|| |:|| |..:.|::|.|                       |:.|.|..    
  Fly   558 -------SMGPQPTAMDQWGAAHAHQHPAA-----------------------YMSTLGLD---- 588

Human   291 GDGAMGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPT 355
             .|.:| ||                     ..|.||      |.:...|.:||||||:.||.|.|
  Fly   589 -KGLLG-GY---------------------TTQGGV------PCFTGSGPIQLWQFLLELLLDKT 624

Human   356 NAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF 420
            ...||:|||.|.||||.:|:||||.|||:||:|.|||:||||.|||||:|.|:.|.||:||||:|
  Fly   625 CQSFISWTGDGWEFKLTDPDEVARRWGIRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRF 689

Human   421 VCEPEALFSLAFPDNQRPALKAEFDRPVSEED 452
            ||:.:.|.... |:.    |.|::|..:.::|
  Fly   690 VCDLQNLVGHT-PEE----LVAKYDLKIEKKD 716

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ETV4NP_001073143.1 ETS_PEA3_N 8..339 CDD:309665 37/177 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 90..115
ETS 341..424 CDD:197710 55/82 (67%)
pntNP_524461.2 SAM_PNT-ETS-1,2 179..250 CDD:188879
ETS 609..693 CDD:197710 55/83 (66%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3806
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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