Protein Alignment ETV4 and etv4

DIOPT Version :10

• Sequence 1: NP_001977.1
• Gene: ETV4 / 2118
• HGNCID: 3493
• Length: 484
• Species: Homo sapiens
• Sequence 2: XP_009304861.2
• Gene: etv4 / 30700
• ZFINID: ZDB-GENE-990415-71
• Length: 495
• Species: Danio rerio
• Alignment Length: 517
• Identity: 304/517 - (58%)
• Similarity: 355/517 - (68%)
• Gaps: 55/517 - (10%)

Human     1 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWL 65
            |:.:|. ||||||||||.:::|.|||.|...|:....|.|| ..|||.:|||||||||..|||||
Zfish     1 MDYKMD-GYLDQQVPYTLANRSQGNGPLNRLLMATKRKYMD-AELPPQESEDLFQDLSQLQETWL 63

Human    66 AEAQVPDSDEQFVPDFHSEN-LAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSA 129
            .||||||||||||||||||| :|||||..:||||||||.:||:.|||.|....|.:||||||:||
Zfish    64 TEAQVPDSDEQFVPDFHSENSVAFHSPPVKIKKEPQSPGSDPSQSCSHKQSFSYPNGEQCLYASA 128

Human   130 YDPPRQIAI-----KSPAPGALGQSPLQ---PFPRA---EQRNFLRSSGTSQPHP--GHGYLGEH 181
            |:..|....     ||..| |...||:|   |.|..   ::..::....:||.|.  .|.|....
Zfish   129 YEQKRAAVAGAGGSKSSCP-ATPMSPMQHYSPKPTVGTRQESGYMNPPSSSQSHACHSHSYPMNP 192

Human   182 SSVFQQ-PLDICHSFTSQGGGREPL-PA--------PYQHQLSEPCPPY-PQQSFKQEYHDPLYE 235
            ||.|.. ..::|..|.|||...:.: ||        .|..|.|:||.|| |||:|||||.||||:
Zfish   193 SSRFPSGSAEMCPPFASQGQALQRMHPAHASGGGGGGYHRQHSDPCLPYPPQQTFKQEYMDPLYD 257

Human   236 QAGQPAVDQGGVNG---HRYPGAGVVIKQEQTDFAYD-SDVTGCASMYLHTEGFSGPSPGDGAMG 296
            :|..       :||   .|:|.|.:::|||.||:.|: :||.||.|||.|.||:|.|.  ..:.|
Zfish   258 RAAH-------INGPQPQRFPPAHMMVKQEPTDYTYEPADVPGCPSMYHHNEGYSNPQ--HNSEG 313

Human   297 YGYEKPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIA 361
            |.:|       :|..||||||||::||||...||||.||||||:||||||||||||||:||||||
Zfish   314 YMFE-------NDSRVVPEKFEGEVKQEGGSVFREGAPYQRRGSLQLWQFLVALLDDPSNAHFIA 371

Human   362 WTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEA 426
            |||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||
Zfish   372 WTGRGMEFKLIEPEEVARLWGMQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEA 436

Human   427 LFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELA----GPAQPFGPKGGYSY 484
            |.:|||||||||:|||||:|.|:||||||||||||..:|.||.|    || ||:..  ||.|
Zfish   437 LITLAFPDNQRPSLKAEFERYVNEEDTVPLSHLDEGVSYPPEPAATNMGP-QPYSK--GYMY 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETV4	NP_001977.1	ETS_PEA3_N	8..339	CDD:461371	176/359 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	90..115		16/24 (67%)
		ETS	341..424	CDD:197710	80/82 (98%)
etv4	XP_009304861.2	None