DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ETV4 and etv4

DIOPT Version :10

Sequence 1:NP_001977.1 Gene:ETV4 / 2118 HGNCID:3493 Length:484 Species:Homo sapiens
Sequence 2:XP_012822986.1 Gene:etv4 / 100486339 XenbaseID:XB-GENE-6051133 Length:365 Species:Xenopus tropicalis


Alignment Length:393 Identity:202/393 - (51%)
Similarity:234/393 - (59%) Gaps:72/393 - (18%)


- Green bases have known domain annotations that are detailed below.


Human    68 AQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSAYDP 132
            ||||||||||..|..|||:.|:||..:||||.|               ..|:...||||:.||..
 Frog    45 AQVPDSDEQFPQDMQSENITFYSPPMKIKKEQQ---------------YRYNSDGQCLYADAYHQ 94

Human   133 PRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGEHSSVFQQPLDICHSFTS 197
            ... .|.||..|: .:|.:..| ..|.|.|....|:.|..|...||.||.|.:.:|:|....|.|
 Frog    95 TGH-GIISPNQGS-QKSQIHYF-STEGRRFAIQQGSIQYAPAEEYLTEHKSRYAEPIDTYLPFQS 156

Human   198 QGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQE 262
            ....||.... ||.|:||||..|.||.||::||:||.|:...    .|.....:.| :.||||||
 Frog   157 LQLSRETSDG-YQSQISEPCLQYLQQEFKEKYHEPLSEEPNH----LGNHKAQQLP-SNVVIKQE 215

Human   263 QTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGVG 327
            |.|::|||                                               .||||||.| 
 Frog   216 QADYSYDS-----------------------------------------------AGDIKQEAV- 232

Human   328 AFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNY 392
            .:|:.|||||||:||||||||||||:|||:|||||||||||||||||||||||||:|||||||||
 Frog   233 PYRDRPPYQRRGSLQLWQFLVALLDNPTNSHFIAWTGRGMEFKLIEPEEVARLWGMQKNRPAMNY 297

Human   393 DKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLS 457
            ||||||||||||||||||||||||||||||:|||||||||.|:|.|:||:|.|..:.||.|||||
 Frog   298 DKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSLAFNDSQCPSLKSESDCRIHEEYTVPLS 362

Human   458 HLD 460
            |||
 Frog   363 HLD 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ETV4NP_001977.1 ETS_PEA3_N 8..339 CDD:461371 95/270 (35%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 90..115 7/24 (29%)
ETS 341..424 CDD:197710 79/82 (96%)
etv4XP_012822986.1 ETS_PEA3_N 45..244 CDD:461371 95/270 (35%)
ETS 245..329 CDD:197710 79/83 (95%)

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