DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ETV3 and Ets97D

DIOPT Version :9

Sequence 1:	NP_001138784.1	Gene:	ETV3 / 2117	HGNCID:	3492	Length:	512	Species:	Homo sapiens
Sequence 2:	NP_001263000.1	Gene:	Ets97D / 43236	FlyBaseID:	FBgn0004510	Length:	484	Species:	Drosophila melanogaster

Alignment Length:	102	Identity:	53/102 - (51%)
Similarity:	67/102 - (65%)	Gaps:	1/102 - (0%)

- Green bases have known domain annotations that are detailed below.

Human    24 YKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYD 88
            |.|..|..:.|:|||.|:||:|...|...||.| .|..|||.:.|||.||||||.:|.||.|||:
  Fly   335 YTTIGSGNNGQVQLWQFLLEILTDCEHTDVIEW-VGTEGEFKLTDPDRVARLWGEKKNKPAMNYE 398

Human    89 KLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVMPNY 125
            ||||||||||:..::.|..||||.|||:.:..::..|
  Fly   399 KLSRALRYYYDGDMISKVSGKRFAYKFDCDLKLLIGY 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ETV3	NP_001138784.1	ETS	34..120	CDD:197710	49/85 (58%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	136..222
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	336..512
Ets97D	NP_001263000.1	GABP-alpha	48..123	CDD:288472
		SAM_PNT-GABP-alpha	184..272	CDD:176084
		ETS	345..429	CDD:197710	49/84 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810