DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ETV2 and Ets97D

DIOPT Version :9

Sequence 1:	XP_005258709.1	Gene:	ETV2 / 2116	HGNCID:	3491	Length:	370	Species:	Homo sapiens
Sequence 2:	NP_001263000.1	Gene:	Ets97D / 43236	FlyBaseID:	FBgn0004510	Length:	484	Species:	Drosophila melanogaster

Alignment Length:	158	Identity:	65/158 - (41%)
Similarity:	86/158 - (54%)	Gaps:	24/158 - (15%)

- Green bases have known domain annotations that are detailed below.

Human   213 PAGPDCTTSWNPGLHAGGTTSL------KRYQSSALTVCSEPSPQSDRASLARCPKT----NHRG 267
            |..|...::.:...::||:.||      |.|||    |.|..|.:|..:|:.....|    .:.|
  Fly   284 PKQPRIMSANSISTNSGGSLSLEQRIMRKSYQS----VKSSDSVESTTSSMNPSNYTTIGSGNNG 344

Human   268 PIQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYR 332
            .:||||||||:|.|...:..|.|.|...||:|.||..|||||||:|.||.||||||||.|||||.
  Fly   345 QVQLWQFLLEILTDCEHTDVIEWVGTEGEFKLTDPDRVARLWGEKKNKPAMNYEKLSRALRYYYD 409

Human   333 RDIVRKSGGRKYTYRFGGRVPSLAYPDC 360
            .|::.|..|:::.|:|          ||
  Fly   410 GDMISKVSGKRFAYKF----------DC 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ETV2	XP_005258709.1	ETS	268..350	CDD:197710	46/81 (57%)
Ets97D	NP_001263000.1	GABP-alpha	48..123	CDD:288472
		SAM_PNT-GABP-alpha	184..272	CDD:176084
		ETS	345..429	CDD:197710	48/93 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243757at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.780