Protein Alignment ETV1 and Ets21C

DIOPT Version :10

• Sequence 1: XP_011513469.1
• Gene: ETV1 / 2115
• HGNCID: 3490
• Length: 491
• Species: Homo sapiens
• Sequence 2: NP_523445.1
• Gene: Ets21C / 33229
• FlyBaseID: FBgn0005660
• Length: 475
• Species: Drosophila melanogaster
• Alignment Length: 502
• Identity: 119/502 - (23%)
• Similarity: 170/502 - (33%)
• Gaps: 172/502 - (34%)

Human    28 NESQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAEAQVPDNDEQFVPDYQAES 92
            :::.|...|.::|.|...:....:.:...:|...:         ..|.:||.|
  Fly    18 SQTIRSAWCQQRPINAMHQDVRQKSIGSGNETKLE---------AKETEVPTN------------ 61

Human    93 LAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSST 157
                      ::.....||..|::.|               :.|:|                |||
  Fly    62 ----------RRRRRRRCSSSSTSDS---------------SASSY----------------SST 85

Human   158 PVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGR 222
            ........|.:|..:..|....|..||.:...|                |..|.|.....||...
  Fly    86 DSDSGSSTSSSSIRSQLPALNLPVPLPLATPTP----------------PAVSSPHQAPSPRRNS 134

Human   223 PMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCH 287
            ....|.:|...:|..|..:..|             ..||       .::...|.|..|.| |...
  Fly   135 SDSNRSVSPVEVPVDPHAWTPE-------------DIAS-------WVRWATRKFKLDPE-PDID 178

Human   288 SI---------YMRQEGFLAHPSRTEGCMF--------------EKGPRQFYDDTCVVPEKFDGD 329
            ..         ..|.:.::...||..|.:.              |..| ...||
  Fly   179 RFPKDAQELCDLSRADFWVCAGSRRGGMLLAQHFAISLYHATGRETSP-MLNDD----------- 231

Human   330 IKQEPGMYREGPTYQRR-------GSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVAR 387
               ||..|:.......|       |.:||||||:.||.|.||::.|:|.|:..||:||:|:||||
  Fly   232 ---EPNPYQLLNAASHRLVAQGSGGQIQLWQFLLELLADSSNANAISWEGQSGEFRLIDPDEVAR 293

Human   388 RWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF-------VCDPEA-----LFSMAF 440
            |||.:|.:|.||||||||:|||||:|.||.||.|:||.|||       .|..:|     ..||..
  Fly   294 RWGERKAKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGLMAACQAQAQGGDPASSMLG 358

Human   441 PDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNE 487
            ..|........:.||     ..||.|..:           :.||:::
  Fly   359 SYNHHAGGAMQLGRH-----PPPLHHHPQ-----------HSHPHHQ 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETV1	XP_011513469.1	ETS_PEA3_N	29..347	CDD:461371	54/347 (16%)
		ETS	348..432	CDD:197710	53/90 (59%)
Ets21C	NP_523445.1	SAM_PNT	149..217	CDD:188876	13/88 (15%)
		ETS	254..339	CDD:197710	52/84 (62%)