Protein Alignment ETV1 and ets-8

DIOPT Version :10

• Sequence 1: XP_011513469.1
• Gene: ETV1 / 2115
• HGNCID: 3490
• Length: 491
• Species: Homo sapiens
• Sequence 2: NP_500046.2
• Gene: ets-8 / 183631
• WormBaseID: WBGene00016798
• Length: 141
• Species: Caenorhabditis elegans
• Alignment Length: 334
• Identity: 60/334 - (17%)
• Similarity: 122/334 - (36%)
• Gaps: 80/334 - (23%)

Human    94 TENNVKSLLDCHIIPALLQGLLSPDLKFIEACL---RCLRTIFTSPVTPEELLY-----TDATVI 150
            |:|:..:.::..:.|....|.:.|..:.|...:   .|.:.........|::||     ..:::.
 Worm   184 TDNDEMTYVNLRLNPERYTGYIGPSARRIWEAIYSENCPKHTSEGSCQEEKILYKLVSGLHSSIS 248

Human   151 PHLMA---LLSRSRYTQEYICQIFSHCCKGPD-----HQTILFNHGAVQNIAHLLTSLSYKVR-- 205
            .|:.:   |...:....:.:..::....:.||     :.|.||...||......|....|:..
 Worm   249 VHIASDYLLDEATNLWGQNLTLLYDRVLRYPDRVQNLYFTFLFVLRAVTKAEDYLGEAEYETGNV 313

Human   206 MQALKCFSVL--AFENPQVSMTL-----VNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYM 263
            ::.||..|::  ...:|:.....     ...|..|:..|::..::.::.:.|...:....|  ..
 Worm   314 IEDLKTKSLVKQVVSDPKTKAACPVPFDEAKLWKGQRGPELKQQLEKQFRNISAIMDCVGC--EK 376

Human   264 CRA-GAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAM 327
            ||. |.::.......||.|              ..|.|.:.|.:    ::||||     :.:||:
 Worm   377 CRLWGKLQILGLGTALKIL--------------FTVNGEDNLRH----NLELQR-----NEVIAL 418

Human   328 LADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKL---YASLGANDEDIRKKIIETENMMDRI 389
            :             ..:.||...:|:.|::..||.::   :||.|             .:...||
 Worm   419 M-------------NLLHRLSESVKYVHDMSPAAERIAGGHASSG-------------NSFWQRI 457

Human   390 VTGLSESSV 398
            ||.:::|.|
 Worm   458 VTSIAQSKV 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETV1	XP_011513469.1	ETS_PEA3_N	29..347	CDD:461371	45/278 (16%)
		ETS	348..432	CDD:197710	13/54 (24%)
ets-8	NP_500046.2	ETS	25..115	CDD:197710