Protein Alignment ETS1 and pnt

DIOPT Version :9

• Sequence 1: NP_001137292.1
• Gene: ETS1 / 2113
• HGNCID: 3488
• Length: 485
• Species: Homo sapiens
• Sequence 2: NP_524461.2
• Gene: pnt / 42757
• FlyBaseID: FBgn0003118
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 591
• Identity: 202/591 - (34%)
• Similarity: 265/591 - (44%)
• Gaps: 180/591 - (30%)

Human    55 DEMATQEVPTGLEHCVSDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTET 119
            |..|:.||||.|            |.|||.:...:::.|||:|:.:.||.|:..|.||||:|||.
  Fly   136 DHEASLEVPTAL------------PPLTPGTNRKVNEVLKASFASWEKEVQKCNITKDPREWTEE 188

Human   120 HVRDWVMWAVNEFSLKGVDFQKFC-MNGAALCALGKDCFLELAPDFVGDILWEHLEILQKEDVKP 183
            ||..|:.||.|||||..::...|. |.|.|:..|||:.||.:.|.|.||||||||:||||:..||
  Fly   189 HVIYWLNWAKNEFSLVSMNLDPFYKMKGRAMVDLGKEKFLAITPPFTGDILWEHLDILQKDCEKP 253

Human   184 YQ--VNGVN----------------PAYP------------ESRYTSDYFISYG----------I 208
            .:  |:|.:                ..||            .||.:.||..|.|          .
  Fly   254 NEDIVHGNSFESATTASVCGSDHQVANYPNETHANSNNSSINSRLSMDYVTSAGNSDNKNFHRAT 318

Human   209 EHA--------------QCVPPSEFSE--------------------PSFITESYQTLHPISSEE 239
            .|:              ...||.:...                    |..:.:|....:..||..
  Fly   319 PHSHNGYNTSNTHDRINNSTPPQQQQSQQPTVNGSGSASSNNNNSMLPPAVQQSNNENNNTSSSN 383

Human   240 LLSLKYENDYPSVILRDPLQTDTLQN-----DYFA--------IKQEVVT--------------- 276
            ..:....|:...........::...|     ::.|        :|:|..|
  Fly   384 TNNSSNNNNNSGGSNNSNAGSNNNNNNNNNINFMAAAAIFQHHLKEEPGTQNGNIGGYGGGSNSQ 448

Human   277 -----------PDNMCM-----------GRTSRGKLGGQDS----------FESIES-------- 301
                       |.::..           ||:|.|  ||.:|          .:|.:|
  Fly   449 NDPTDLSSYGLPAHLAAYGGGSGSGPTGGRSSGG--GGDESDYHSTISAQDHQSQQSSGGNGSGG 511

Human   302 ------------YDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDY------PAALPNHKPKGTF 348
                        .||......|::.::.|:. ...|.:..:|::.:      |.|:.........
  Fly   512 ASGGSTGNSNGYLDSSSEFYGSYAGRNRFHD-GYPPEFTPYDAQSFQSMGPQPTAMDQWGAAHAH 575

Human   349 KDYVRDRADLNKDKPVIPAAALAG----YTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKL 409
            :......:.|..||.::......|    :||||||||||||||||.||:||||||||||||||||
  Fly   576 QHPAAYMSTLGLDKGLLGGYTTQGGVPCFTGSGPIQLWQFLLELLLDKTCQSFISWTGDGWEFKL 640

Human   410 SDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELH 474
            :||||||||||.||||||||||||||||||||||||||||||||||||||||||:|:|:|||||.
  Fly   641 TDPDEVARRWGIRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQNLVGHTPEELV 705

Human   475 AMLDVK 480
            |..|:|
  Fly   706 AKYDLK 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETS1	NP_001137292.1	SAM_PNT-ETS-1	95..182	CDD:176092	46/87 (53%)
		ETS	378..462	CDD:197710	79/83 (95%)
pnt	NP_524461.2	SAM_PNT-ETS-1,2	179..250	CDD:188879	40/70 (57%)
		ETS	609..693	CDD:197710	79/83 (95%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	168	1.000	Domainoid score	I3832
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	325	1.000	Inparanoid score	I2492
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243757at33208
OrthoFinder	1	1.000	-	-		FOG0003547
OrthoInspector	1	1.000	-	-		otm40489
orthoMCL	1	0.900	-	-		OOG6_107578
Panther	1	1.100	-	-	O	PTHR11849
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10367
SonicParanoid	1	1.000	-	-		X2422
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.860