Protein Alignment ETS1 and Eip74EF

DIOPT Version :10

• Sequence 1: XP_047282481.1
• Gene: ETS1 / 2113
• HGNCID: 3488
• Length: 502
• Species: Homo sapiens
• Sequence 2: NP_730288.1
• Gene: Eip74EF / 39962
• FlyBaseID: FBgn0000567
• Length: 883
• Species: Drosophila melanogaster
• Alignment Length: 568
• Identity: 122/568 - (21%)
• Similarity: 176/568 - (30%)
• Gaps: 180/568 - (31%)

Human    39 VVRQGPSNTYEDPRMNCGFQSNYH-----QQRPCYPFWDEMATQEVPTGLEHCVSDMECADVPLL 98
            :|:|..|     |......|..:|     ||:|     ...:|....|.|.|..::..    .||
  Fly   352 IVKQSTS-----PAPQQQLQQQHHLQQQQQQQP-----HNGSTFAGATALLHIKTEQN----TLL 402

Human    99 TP---SSKEMMSQALK-ATFSGFT-------KEQQRLGIPKDPRQWT--------ETHVRDWVMW 144
            ||   ..::...|.|. |..:|.:       ::||.|.||:.|....        ..|.|::...
  Fly   403 TPLQLQQQQQQQQGLHGAAGNGGSSNGNNAHQQQQPLAIPQRPLLHNLLSGGAIHNPHHRNYTTA 467

Human   145 AVNEF----SLKGVDFQKFCMNGAALCALGKDCFLELAPD-------------------FVGDIL 186
            ....|    :..||.......:|...||......|.:.|.                   ..|..|
  Fly   468 TTGSFPPSPADSGVSDVDSSSSGGQPCADELKARLGMPPATSASAAAAAAAAAAAAAHLHTGTFL 532

Human   187 WEHLEILQKEDVKPYQVNGVNP---------AYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFI 242
            ..:|          ||.|..|.         ..|::.|.|.   ..|....|...|.....|.::
  Fly   533 HPNL----------YQNNAANSLRNIWNRSVGVPDNYYGSS---GAGSGGTQPGGPGNPQTPGYL 584

Human   243 TESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKL 307
            |.||                 .:.|:.......|..|..|.|.::.|:     .....::.:.:.
  Fly   585 TTSY-----------------FNAPTAATAAASQRGTTINGYHSLHQQ-----QQQQQQSQQSQQ 627

Human   308 GGQDSFESIESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPNHKPK---------- 362
            ..|.:.:.: |:.....|.|..|.|......|:.....|..:..:|.:.|:..|.
  Fly   628 QQQLAHQQL-SHQQQQALHQQLSHQQQQQQQQQQQHPHSQLNGPHPHSHPHSHPHSHPHAGQHTH 691

Human   363 ---------------GTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQ--------------- 397
                           .:....|...|.|:........||.|.......||
  Fly   692 STIAAAAAAAAASVVSSSSSAVAAAAMLSASAAAAATAAAAAGGSQSVIQPATSSVSYDLSYMLE 756

Human   398 --------------------------------LWQFLLELLTDKS-CQSFISWTG-DGWEFKLSD 428
                                            ||:|||:||.|:. |..||.||. :...|||.|
  Fly   757 LGGFQQRKAKKPRKPKLEMGVKRRSREGSTTYLWEFLLKLLQDREYCPRFIKWTNREKGVFKLVD 821

Human   429 PDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFV 476
            ...|:|.||..||||.||||.:.|.|||||.:.|:.|..|:|.||:||
  Fly   822 SKAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFV 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETS1	XP_047282481.1	SAM_PNT-ETS-1	112..199	CDD:176092	21/124 (17%)
		Ets1_N_flank	208..395	CDD:466113	33/220 (15%)
		ETS	395..479	CDD:197710	45/131 (34%)
Eip74EF	NP_730288.1	ETS	786..872	CDD:197710	43/84 (51%)