Protein Alignment ETFDH and Etfdh

DIOPT Version :9

• Sequence 1: NP_004444.2
• Gene: ETFDH / 2110
• HGNCID: 3483
• Length: 617
• Species: Homo sapiens
• Sequence 2: NP_080070.2
• Gene: Etfdh / 66841
• MGIID: 106100
• Length: 616
• Species: Mus musculus
• Alignment Length: 617
• Identity: 570/617 - (92%)
• Similarity: 591/617 - (95%)
• Gaps: 1/617 - (0%)

Human     1 MLVPLAKLSCLAYQCFHALKIKKNYLPLCATRWSSTSTVPRITTHYTIYPRDKDKRWEGVNMERF 65
            |||.|.||||.||..|||||||| .|||||.|.||||.||:||||||::||:|||||||||||||
Mouse     1 MLVRLTKLSCPAYHWFHALKIKK-CLPLCAPRCSSTSAVPQITTHYTVHPREKDKRWEGVNMERF 64

Human    66 AEEADVVIVGAGPAGLSAAVRLKQLAVAHEKDIRVCLVEKAAQIGAHTLSGACLDPGAFKELFPD 130
            |||||||||||||||||||:||||||....||||||||||||||||||||||||||.||||||||
Mouse    65 AEEADVVIVGAGPAGLSAAIRLKQLAAEQGKDIRVCLVEKAAQIGAHTLSGACLDPAAFKELFPD 129

Human   131 WKEKGAPLNTPVTEDRFGILTEKYRIPVPILPGLPMNNHGNYIVRLGHLVSWMGEQAEALGVEVY 195
            |||||||||||||||||.|||||:|||||||||||||||||||||||||||||||||||||||||
Mouse   130 WKEKGAPLNTPVTEDRFAILTEKHRIPVPILPGLPMNNHGNYIVRLGHLVSWMGEQAEALGVEVY 194

Human   196 PGYAAAEVLFHDDGSVKGIATNDVGIQKDGAPKATFERGLELHAKVTIFAEGCHGHLAKQLYKKF 260
            |||||||||:|:|||||||||||||||||||||.|||||||||||||:|||||||||||||||||
Mouse   195 PGYAAAEVLYHEDGSVKGIATNDVGIQKDGAPKTTFERGLELHAKVTVFAEGCHGHLAKQLYKKF 259

Human   261 DLRANCEPQTYGIGLKELWVIDEKNWKPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLVALGLVV 325
            ||||:|:.|||||||||||:||||.|||||||||||||||||||||||||||||||||||:|.||
Mouse   260 DLRASCDAQTYGIGLKELWIIDEKKWKPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLVAVGFVV 324

Human   326 GLDYQNPYLSPFREFQRWKHHPSIRPTLEGGKRIAYGARALNEGGFQSIPKLTFPGGLLIGCSPG 390
            ||||||||||||||||||||||||:||||||||||||||||||||.|||||||||||||||||||
Mouse   325 GLDYQNPYLSPFREFQRWKHHPSIQPTLEGGKRIAYGARALNEGGLQSIPKLTFPGGLLIGCSPG 389

Human   391 FMNVPKIKGTHTAMKSGILAAESIFNQLTSENLQSKTIGLHVTEYEDNLKNSWVWKELYSVRNIR 455
            |||||||||||||||||.|||||||.|||||||||||.||||||||||||.|||||||::|||||
Mouse   390 FMNVPKIKGTHTAMKSGSLAAESIFKQLTSENLQSKTTGLHVTEYEDNLKQSWVWKELHAVRNIR 454

Human   456 PSCHGVLGVYGGMIYTGIFYWILRGMEPWTLKHKGSDFERLKPAKDCTPIEYPKPDGQISFDLLS 520
            |||||:|||||||||||||||||||||||||||||||.::|||||||||||||||||||||||||
Mouse   455 PSCHGILGVYGGMIYTGIFYWILRGMEPWTLKHKGSDSDQLKPAKDCTPIEYPKPDGQISFDLLS 519

Human   521 SVALSGTNHEHDQPAHLTLRDDSIPVNRNLSIYDGPEQRFCPAGVYEFVPVEQGDGFRLQINAQN 585
            |||||||||||||||||||:||||||||||||||||||||||||||||||:||||||||||||||
Mouse   520 SVALSGTNHEHDQPAHLTLKDDSIPVNRNLSIYDGPEQRFCPAGVYEFVPLEQGDGFRLQINAQN 584

Human   586 CVHCKTCDIKDPSQNINWVVPEGGGGPAYNGM 617
            ||||||||||||||||||||||||||||||||
Mouse   585 CVHCKTCDIKDPSQNINWVVPEGGGGPAYNGM 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETFDH	NP_004444.2	FixC	67..529	CDD:223717	430/461 (93%)
		NADB_Rossmann	68..>217	CDD:304358	138/148 (93%)
		ETF_QO	512..615	CDD:282972	100/102 (98%)
Etfdh	NP_080070.2	FixC	66..528	CDD:223717	430/461 (93%)
		NADB_Rossmann	67..>261	CDD:304358	181/193 (94%)
		ETF_QO	511..614	CDD:282972	100/102 (98%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83968648
Domainoid	1	1.000	794	1.000	Domainoid score	I2906
eggNOG	1	0.900	-	-		E1_COG2440
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3275
Inparanoid	1	1.050	1200	1.000	Inparanoid score	I4381
Isobase	1	0.950	-	0	Normalized mean entropy	S422
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG54178
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003019
OrthoInspector	1	1.000	-	-		oto121498
orthoMCL	1	0.900	-	-		OOG6_101719
Panther	1	1.100	-	-	LDO	PTHR10617
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3366
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	17.210