Protein Alignment ETFDH and etfdh

DIOPT Version :9

• Sequence 1: NP_004444.2
• Gene: ETFDH / 2110
• HGNCID: 3483
• Length: 617
• Species: Homo sapiens
• Sequence 2: NP_001005631.1
• Gene: etfdh / 448088
• XenbaseID: XB-GENE-972267
• Length: 616
• Species: Xenopus tropicalis
• Alignment Length: 617
• Identity: 513/617 - (83%)
• Similarity: 567/617 - (91%)
• Gaps: 2/617 - (0%)

Human     2 LVPLAKLSCLAYQCFHALKIKKNYLP-LCATRWSSTSTVPRITTHYTIYPRDKDKRWEGVNMERF 65
            ::||.|.:..|:.||......||.|| .|..||:| |:||||||||||.|||:||||||:|||||
 Frog     1 MLPLCKHTLHAHHCFAYFTALKNCLPSSCLKRWAS-SSVPRITTHYTICPRDQDKRWEGMNMERF 64

Human    66 AEEADVVIVGAGPAGLSAAVRLKQLAVAHEKDIRVCLVEKAAQIGAHTLSGACLDPGAFKELFPD 130
            ||||||||||.||||||||:||||||...:|::|||||||.|||||||||||||:|.|.:|||||
 Frog    65 AEEADVVIVGGGPAGLSAAIRLKQLAAECDKELRVCLVEKGAQIGAHTLSGACLEPRALEELFPD 129

Human   131 WKEKGAPLNTPVTEDRFGILTEKYRIPVPILPGLPMNNHGNYIVRLGHLVSWMGEQAEALGVEVY 195
            |||:|||||||||||:|||||:|:||||||||||||||||||||||||.|||:||||||||||:|
 Frog   130 WKERGAPLNTPVTEDKFGILTKKHRIPVPILPGLPMNNHGNYIVRLGHFVSWLGEQAEALGVEIY 194

Human   196 PGYAAAEVLFHDDGSVKGIATNDVGIQKDGAPKATFERGLELHAKVTIFAEGCHGHLAKQLYKKF 260
            |||||:|||||:||||||||||||||.|||:||:|||||||||||||||.||||||||||||.||
 Frog   195 PGYAASEVLFHEDGSVKGIATNDVGIHKDGSPKSTFERGLELHAKVTIFGEGCHGHLAKQLYNKF 259

Human   261 DLRANCEPQTYGIGLKELWVIDEKNWKPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLVALGLVV 325
            :||.|||||||.||||||||||||.||||.|:|||||||||||||||||||||||||||||||||
 Frog   260 NLRQNCEPQTYAIGLKELWVIDEKKWKPGCVEHTVGWPLDRHTYGGSFLYHLNEGEPLVALGLVV 324

Human   326 GLDYQNPYLSPFREFQRWKHHPSIRPTLEGGKRIAYGARALNEGGFQSIPKLTFPGGLLIGCSPG 390
            |||||||:::||||.||||||||:.||||||.||||||||||||||||:||||||||:|:|||||
 Frog   325 GLDYQNPFINPFRELQRWKHHPSVVPTLEGGNRIAYGARALNEGGFQSLPKLTFPGGILVGCSPG 389

Human   391 FMNVPKIKGTHTAMKSGILAAESIFNQLTSENLQSKTIGLHVTEYEDNLKNSWVWKELYSVRNIR 455
            |||||||||||||||||:||||:||.:||.|::||||.||.|.|||::||.||:|||||||||||
 Frog   390 FMNVPKIKGTHTAMKSGMLAAENIFKKLTDESIQSKTQGLDVPEYEESLKKSWIWKELYSVRNIR 454

Human   456 PSCHGVLGVYGGMIYTGIFYWILRGMEPWTLKHKGSDFERLKPAKDCTPIEYPKPDGQISFDLLS 520
            |||||.||:||||:|||||||:|||.|||||||||.|..:|||||||.|||||||||::||||||
 Frog   455 PSCHGPLGLYGGMVYTGIFYWMLRGKEPWTLKHKGLDSNQLKPAKDCVPIEYPKPDGKLSFDLLS 519

Human   521 SVALSGTNHEHDQPAHLTLRDDSIPVNRNLSIYDGPEQRFCPAGVYEFVPVEQGDGFRLQINAQN 585
            |||||||||:|||||||||:|||:|||:||:|||||||||||||||||||:|.|:|.||||||||
 Frog   520 SVALSGTNHDHDQPAHLTLKDDSLPVNKNLAIYDGPEQRFCPAGVYEFVPLESGEGSRLQINAQN 584

Human   586 CVHCKTCDIKDPSQNINWVVPEGGGGPAYNGM 617
            ||||||||||||||||||||||||||||||||
 Frog   585 CVHCKTCDIKDPSQNINWVVPEGGGGPAYNGM 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETFDH	NP_004444.2	FixC	67..529	CDD:223717	392/461 (85%)
		NADB_Rossmann	68..>217	CDD:304358	126/148 (85%)
		ETF_QO	512..615	CDD:282972	91/102 (89%)
etfdh	NP_001005631.1	FixC	66..528	CDD:223717	392/461 (85%)
		ETF_QO	511..614	CDD:368327	91/102 (89%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	728	1.000	Domainoid score	I1529
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3275
Inparanoid	1	1.050	1104	1.000	Inparanoid score	I2611
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG54178
OrthoDB	1	1.010	-	-		D117499at7742
OrthoFinder	1	1.000	-	-		FOG0003019
OrthoInspector	1	1.000	-	-		oto154662
Panther	1	1.100	-	-	LDO	PTHR10617
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3366
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.080