Protein Alignment ESRRG and usp

DIOPT Version :9

• Sequence 1: XP_011507567.1
• Gene: ESRRG / 2104
• HGNCID: 3474
• Length: 477
• Species: Homo sapiens
• Sequence 2: NP_001259168.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Alignment Length: 495
• Identity: 140/495 - (28%)
• Similarity: 221/495 - (44%)
• Gaps: 88/495 - (17%)

Human    44 DSSCSSFI-KTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSG 107
            ||:.|||. |.|...|.....|:.|..||.:|.:|.:.|:   |......:|   .||   |||
  Fly    28 DSNNSSFSPKAESPVPFMQAMSMVHVLPGSNSASSNNNSA---GDAQMAQAP---NSA---GGS- 82

Human   108 PVRKLYDDCSSTIVEDPQTKCEYMLN---SMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQ 169
                     ::..|:.     :|..|   |..|.||.:|||.|||.||||.|||.||.|||||::
  Fly    83 ---------AAAAVQQ-----QYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFKRTVR 133

Human   170 GNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYL 234
            .::.|:|.....|.|.||:|..||.||:.|||..||.:|.|:.:|.||.|.. ..|:.|......
  Fly   134 KDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGMKREAVQEERQRGARNA-AGRLSASGGGSS 197

Human   235 NPQLVQPAKK--------------------PLLWSDPADNKIVSHLLVAEPEK-----------I 268
            .|..|..:..                    ..:.:..:.:..:..::.||...           :
  Fly   198 GPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDFMTNSVSRDFSIERIIEAEQRAETQCGDRALTFL 262

Human   269 YAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVV 333
            ...|..||......|::.||.:.:::|..::.:|:.:|.|:.:.|.||:.||::||:|:||..|.
  Fly   263 RVGPYSTVQPDYKGAVSALCQVVNKQLFQMVEYARMMPHFAQVPLDDQVILLKAAWIELLIANVA 327

Human   334 YRSL-------------------SFE--------DELVYADDYIMDEDQSKLAGLLDLNNAIL-Q 370
            :.|:                   |||        .:|.....:....:.:..||:..:.:.|| :
  Fly   328 WCSIVSLDDGGAGGGGGGLGHDGSFERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAIFDRILSE 392

Human   371 LVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGK 435
            |..|.|.:.|::.|...||||.|.|.|...|:....::..::.::..|.::...:|..|..|..:
  Fly   393 LSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAEIEMCREKVYACLDEHCRLEHPGDDGRFAQ 457

Human   436 MLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEA 475
            :|:.||.||..|.|...|.:..::....|:.:||||.|||
  Fly   458 LLLRLPALRSISLKCQDHLFLFRITSDRPLEELFLEQLEA 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ESRRG	XP_011507567.1	NR_DBD_ERR	134..230	CDD:143544	48/95 (51%)
		NR_LBD_ERR	256..475	CDD:132744	63/257 (25%)
usp	NP_001259168.1	NR_DBD_RXR	102..178	CDD:143514	40/75 (53%)
		NR_LBD_RXR_like	237..480	CDD:132741	57/242 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1511
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.860