Protein Alignment ESRRA and esrra

DIOPT Version :10

• Sequence 1: XP_016872802.1
• Gene: ESRRA / 2101
• HGNCID: 3471
• Length: 433
• Species: Homo sapiens
• Sequence 2: XP_005161401.1
• Gene: esrra / 405891
• ZFINID: ZDB-GENE-990415-68
• Length: 441
• Species: Danio rerio
• Alignment Length: 442
• Identity: 279/442 - (63%)
• Similarity: 323/442 - (73%)
• Gaps: 46/442 - (10%)

Human    21 LYIKAEPASPD----------SPKGSSETETE---------------PPVALAPGPAPTRCLPGH 60
            |||||||:||:          ||.|:|...::               ||:..   || .||   |
Zfish    15 LYIKAEPSSPEGGGGGGGGRTSPGGASSDSSQSGGGGSRGEGAGRYSPPLYT---PA-LRC---H 72

Human    61 KEEEDGEGAGPGEQGGG----KLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSI 121
            .:||..:||..|..|.|    |..||:||||||||||||||||||||||||||||||||||||:|
Zfish    73 FKEEGADGAEEGSTGSGGGRCKYALSTLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGNI 137

Human   122 EYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPF 186
            |||||||||||||||||||||||||||||:||||||||||||||||||||||||||:    ...:
Zfish   138 EYSCPASNECEITKRRRKACQACRFTKCLKVGMLKEGVRLDRVRGGRQKYKRRPEVE----NATY 198

Human   187 PAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTIS 251
            .:.|:.:.....|.::.:  :||||||.|||||:|||||..||.....:.|||||.|||:||.|.
Zfish   199 QSAPIPLRKEGEKGSSSI--IVSHLLVAEPEKLFAMPDPLQPDTAQRTLTTLCDLADRELVVIIG 261

Human   252 WAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELG 316
            |||.||||.||||:||||||||||:||||||||.|||..:||:.||||.|||||.:|.|||.||.
Zfish   262 WAKHIPGFLSLSLADQMSVLQSVWLEVLVLGVAYRSLGCEDEVVFAEDFVLDEEMSRVAGLTELN 326

Human   317 AALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGG 381
            ||:.||.||.:||:|:|||:|:|||:||.|||||:|||.|||::||:.||:||||.|..|...
Zfish   327 AAISQLARRFRALQLDREEFVMLKAIALTNSDSVYIEDMEAVQKLRDLLHQALLELEVQRRPD-- 389

Human   382 GAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD 433
              :.:|||||||||||||||||:.|..||.:|..|.||||||||||||||||
Zfish   390 --DPQRAGRLLLTLPLLRQTAGRALTTFYSIKTRGGVPMHKLFLEMLEAMMD 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ESRRA	XP_016872802.1	NR_DBD_ERR	83..178	CDD:143544	91/94 (97%)
		NR_LBD_ERR	207..430	CDD:132744	150/222 (68%)
esrra	XP_005161401.1	NR_DBD_ERR	99..195	CDD:143544	92/99 (93%)
		NR_LBD_ERR	217..436	CDD:132744	150/222 (68%)