Protein Alignment ESRRA and Esrra

DIOPT Version :10

• Sequence 1: XP_016872802.1
• Gene: ESRRA / 2101
• HGNCID: 3471
• Length: 433
• Species: Homo sapiens
• Sequence 2: NP_031979.2
• Gene: Esrra / 26379
• MGIID: 1346831
• Length: 422
• Species: Mus musculus
• Alignment Length: 423
• Identity: 415/423 - (98%)
• Similarity: 416/423 - (98%)
• Gaps: 1/423 - (0%)

Human    11 MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQG 75
            |||||||||||||||||||||||||||||||||||.||.||||.||||||||||||||||.||||
Mouse     1 MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVTLASGPAPARCLPGHKEEEDGEGAGSGEQG 65

Human    76 GGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKA 140
            .||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 SGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKA 130

Human   141 CQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVN 205
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| ||||
Mouse   131 CQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKT-APVN 194

Human   206 ALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSV 270
            |||||||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||
Mouse   195 ALVSHLLVVEPEKLYAMPDPASPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSV 259

Human   271 LQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREE 335
            |||||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||||
Mouse   260 LQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGDLGAALLQLVRRLQALRLEREE 324

Human   336 YVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQ 400
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   325 YVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQ 389

Human   401 TAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD 433
            |||||||||||||||||||||||||||||||||
Mouse   390 TAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ESRRA	XP_016872802.1	NR_DBD_ERR	83..178	CDD:143544	94/94 (100%)
		NR_LBD_ERR	207..430	CDD:132744	220/222 (99%)
Esrra	NP_031979.2	Repressor domain	1..76		69/74 (93%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..66		60/64 (94%)
		NR_DBD_ERR	73..168	CDD:143544	94/94 (100%)
		NR_LBD_ERR	196..419	CDD:132744	220/222 (99%)
		AF-2 domain. /evidence=ECO:0000250	402..422		19/19 (100%)