Protein Alignment Znrf4 and C18B12.4

DIOPT Version :9

• Sequence 1: NP_035613.2
• Gene: Znrf4 / 20834
• MGIID: 1341258
• Length: 327
• Species: Mus musculus
• Sequence 2: NP_510498.1
• Gene: C18B12.4 / 181600
• WormBaseID: WBGene00007666
• Length: 456
• Species: Caenorhabditis elegans
• Alignment Length: 306
• Identity: 80/306 - (26%)
• Similarity: 118/306 - (38%)
• Gaps: 90/306 - (29%)

Mouse    45 GVPVDPKRARGYLLVAR-PADACH---------AIEGPWPDNH-------SLDPLVLV------- 85
            ||.|:|..|.|.:.:|: ....||         .|..|...:|       |..|..||
 Worm    70 GVGVEPVDACGPVRIAQNHTTRCHNLFAFVSRSNISHPCKFSHQAFMVQNSTYPFRLVIFYNYPG 134

Mouse    86 -RPLGCSWEQTGRRAQRAGATAASVGPEAPGQL-REFED---LEVTVRCD----QPARVLLPHAE 141
             .|:  |.|.|..| .:.......:......:: ::|.|   ..:.||.|    :..|.|:|.
 Worm   135 QEPI--SMEGTELR-DKVNIPVLMISHACKEEIAKKFSDTAGYRLRVRIDPGYYELFRYLIPF-- 194

Mouse   142 PCPDPECHPVVVASWALARALALAASTLFVLRQLWPWVRGLGSRGTAVK----TQTCQKAQVRTF 202
                     :||..:..|         ||::...   |||...|....|    .:..:|..|:.:
 Worm   195 ---------LVVIVFCFA---------LFLITLC---VRGCVERRKLNKRRLSKRNLKKIPVKKY 238

Mouse   203 TRLS---DLCAICLDDYEEGERLKILPCAHAYHCRCIDPWFSRAAQRSCPLCKQSV--------- 255
             ||.   |.|||||:.:..||:|:.|||.|.:||.|||.|.:: .::.|||||:.:
 Worm   239 -RLGDDPDTCAICLESFASGEKLRHLPCRHVFHCNCIDVWLTQ-TRKICPLCKRKIGTDSDSECS 301

Mouse   256 ----ASTHDGSTDGSV--------GGEEPPLP-GHRPPIWAIQARL 288
                |||..|..|.:.        .|.|.|:| |....:|:.|..|
 Worm   302 TNDLASTSQGPNDATALYNNADNQSGFELPVPQGQMVDLWSSQEAL 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Znrf4	NP_035613.2	PA_C_RZF_like	19..156	CDD:239038	31/143 (22%)
		zf-RING_2	207..252	CDD:290367	22/44 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	256..279		10/31 (32%)
C18B12.4	NP_510498.1	PA	<74..176	CDD:333703	20/104 (19%)
		HRD1	<223..>335	CDD:227568	37/113 (33%)
		RING-H2_RNF103	246..291	CDD:319387	23/45 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	75	1.000	Domainoid score	I6375
eggNOG	1	0.900	-	-		E1_KOG4628
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770