DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Srms and wnd

DIOPT Version :9

Sequence 1:	NP_035611.3	Gene:	Srms / 20811	MGIID:	101865	Length:	507	Species:	Mus musculus
Sequence 2:	NP_649137.3	Gene:	wnd / 40143	FlyBaseID:	FBgn0036896	Length:	977	Species:	Drosophila melanogaster

Alignment Length:	255	Identity:	78/255 - (30%)
Similarity:	129/255 - (50%)	Gaps:	15/255 - (5%)

- Green bases have known domain annotations that are detailed below.

Mouse   236 DEWERPRSEFVLRRKLGEGFFGEVWEGLWLGSIPVAVKVIKSADMKLADLTKEIEALKSLRHERL 300
            ::|:.|.........||.|..|.|:.|. |.:..||||.:|  ::|..|    |:.|:.|.||.:
  Fly   152 EDWQIPFESITELEWLGSGAQGAVFSGR-LKNETVAVKKVK--ELKETD----IKHLRKLDHENI 209

Mouse   301 IRLHAICSLGEPVYIVTELMGKGNLQVYLGSSEGKALSLP-HLLGFACQVAEGMSYLEERRVVHR 364
            |:...:|:......|:.|....|.||..|...:   :.|| .|:.::.|:|.||.||...:::||
  Fly   210 IKFKGVCTQSPVFCIIMEFCPYGPLQNILKEEQ---VMLPSRLVSWSKQIALGMQYLHSHKIIHR 271

Mouse   365 DLAARNVLVGDDLTCKVADFGLARLLKDDVYSPSSGSKIPVKWTAPEAANYRVFSQKSDVWSFGI 429
            ||.:.|:|:..:...|::|||.:|...:  .|........|.|.|||.......|:|.|:||:|:
  Fly   272 DLKSPNILISTNEVVKISDFGTSREWNE--ISTKMSFAGTVAWMAPEVIRNEPCSEKVDIWSYGV 334

Mouse   430 LLYEVFTYGQCPYEGMTNHETLQQI-SRGYRLPRPAVCPAEVYVLMVECWKGSPEERPTF 488
            :|:|:.|. :.||:.:.:...:..: :...:|..|:.||....:|:..|||..|..||:|
  Fly   335 VLWEMLTC-EIPYKDVDSSAIIWGVGNNSLKLLVPSTCPEGFKLLVKLCWKSKPRNRPSF 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Srms	NP_035611.3	SH3	70..124	CDD:302595
		SH2_Srm	134..212	CDD:198223
		PTKc_Srm_Brk	238..498	CDD:133248	78/253 (31%)
		STYKc	246..495	CDD:214568	76/245 (31%)
wnd	NP_649137.3	STYKc	161..400	CDD:214568	76/246 (31%)
wnd	NP_649137.3	STKc_MAP3K12_13	167..403	CDD:270961	76/240 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910