Protein Alignment ERN1 and ern1

DIOPT Version :9

• Sequence 1: XP_016879836.1
• Gene: ERN1 / 2081
• HGNCID: 3449
• Length: 1014
• Species: Homo sapiens
• Sequence 2: NP_001018366.1
• Gene: ern1 / 553551
• ZFINID: ZDB-GENE-050522-431
• Length: 292
• Species: Danio rerio
• Alignment Length: 275
• Identity: 217/275 - (78%)
• Similarity: 246/275 - (89%)
• Gaps: 5/275 - (1%)

Human    42 LWELHSWKIPHGFEIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVE 106
            :|..||     |...|.|:|||::||:|||||||||:||||||.:|:|||||||||||||||||.
Zfish    18 IWWSHS-----GLMGFCSSSTVSVPESLLFVSTLDGNLHAVSKISGTIKWTLKEDPVLQVPTHVS 77

Human   107 EPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGE 171
            ||||||||||||||:||.||||||||||||||||||||||||||||||||||||:.||:||||||
Zfish    78 EPAFLPDPNDGSLYSLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDVRYVVDLLTGE 142

Human   172 KQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPEDDVDYKMSHFV 236
            |:|||:|::|:.||||:||.|||||||||||||||:|||||||||.|||.:||::|..|.|:|||
Zfish   143 KKQTLTSSYAEMLCPSSSLFYLGRTEYTITMYDTKSRELRWNATYSDYAFTLPDEDTKYNMAHFV 207

Human   237 SNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRIT 301
            |||||||||||||||||.|:|||.|||||.|:|||||||||.|.|||||||||||||||||||||
Zfish   208 SNGDGLVVTVDSESGDVQWVQNYNSPVVAVYIWQREGLRKVPHTNVAVETLRYLTFMSGEVGRIT 272

Human   302 KWKYPFPKETEAKSK 316
            :||||||:|.:.:|:
Zfish   273 QWKYPFPREKKKESQ 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERN1	XP_016879836.1	None
ern1	NP_001018366.1	PQQ_2	16..228	CDD:290097	169/214 (79%)
		Luminal_IRE1	38..265	CDD:188875	190/226 (84%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	741	1.000	Domainoid score	I983
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1406	1.000	Inparanoid score	I1121
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48078
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001857
OrthoInspector	1	1.000	-	-		oto43598
orthoMCL	1	0.900	-	-		OOG6_102150
Panther	1	1.100	-	-	O	PTHR13954
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2163
SonicParanoid	1	1.000	-	-		X1217
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	1	1.500	-	-
	13	13.500