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Protein Alignment AKT2 and YPK1

DIOPT Version :9

Sequence 1:	NP_001617.1	Gene:	AKT2 / 208	HGNCID:	392	Length:	481	Species:	Homo sapiens
Sequence 2:	NP_012796.1	Gene:	YPK1 / 853733	SGDID:	S000001609	Length:	680	Species:	Saccharomyces cerevisiae

Alignment Length:	337	Identity:	153/337 - (45%)
Similarity:	219/337 - (64%)	Gaps:	19/337 - (5%)

- Green bases have known domain annotations that are detailed below.

Human   120 MDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILR 184
            :|||   ||.:.              .::::|||.||::|||:||||:.||:|.|.:.||:|.:|
Yeast   332 IDYK---PSRNK--------------PLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIR 379

Human   185 KEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTE 249
            |..|::|.||.||:.|..||.....||:..||::||:.::|.||:.:.||||||:||.:|..|..
Yeast   380 KSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDL 444

Human   250 ERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTP 314
            .|||||.||::.||:.||..||||||:|.||::||..|||.:.||||||..:.|.....||||||
Yeast   445 SRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTP 509

Human   315 EYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKS 379
            ||||||:|....|.:|||||.|||::|||:.|..|:|::|..::::.||.|.:.||.....:||.
Yeast   510 EYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKD 574

Human   380 LLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFT 444
            ||.|||.:||.:|||...:|  |:..|.||..::|:.::.|..:||:||.|::.:||..||:|||
Yeast   575 LLIGLLSRDPTRRLGYNGAD--EIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFT 637

Human   445 AQSITITPPDRY 456
            .:....:..|.|
Yeast   638 REKPIDSVVDEY 649

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.