Protein Alignment AKT2 and CG32944

DIOPT Version :10

• Sequence 1: NP_001617.1
• Gene: AKT2 / 208
• HGNCID: 392
• Length: 481
• Species: Homo sapiens
• Sequence 2: NP_788574.3
• Gene: CG32944 / 40560
• FlyBaseID: FBgn0052944
• Length: 576
• Species: Drosophila melanogaster
• Alignment Length: 311
• Identity: 107/311 - (34%)
• Similarity: 160/311 - (51%)
• Gaps: 15/311 - (4%)

Human   127 PSDSSTTEEMEVAVSKARAKVTMN--DFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVII 189
            |.|.|......:.| |.::.:.:|  .|..|:.:|||:||||.:|:::.||..||||.:.:....
  Fly   125 PEDHSLAMGHMLCV-KCQSLIPINFDHFQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACE 188

Human   190 AKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARF 254
            .:..:...:.|..:|.:..||||..|.::||..:.|..|.:...||:|.:||.....|:|:....
  Fly   189 MRGALGGVIKEVELLSSLEHPFLVNLWFSFQDEEDLFMVCDLLTGGDLRYHLQNRVEFSEQSVAL 253

Human   255 YGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAP 319
            ...|:.||||||.:..||:||||.:|::||..||..:|||.:... :...|...:..||..|:||
  Fly   254 LVCELGSALEYLQANRVVHRDIKPDNILLDDAGHAHLTDFNIATR-LQKNALACSMSGTKPYMAP 317

Human   320 EVL-----EDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFEL--ILMEEIRFPRTLSPEA 377
            ||.     |...|...||||.||||.|||.....||....:..|.|:  ||...:.:||..|...
  Fly   318 EVFLCALDEVAGYSYPVDWWSLGVVAYEMRGNIRPFVVHSNTPLAEIKNILNTPVHYPRYWSSNF 382

Human   378 KSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKP 428
            ..||..||...|..|:    |..:|:.:.....:|::|.|::||:.|.:||
  Fly   383 VDLLQRLLSTYPGARI----STRQELHQTPMLRNIDFQRVLEKKIKPIYKP 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AKT2	NP_001617.1	PH_PKB	4..111	CDD:269947
		STKc_PKB_beta	156..478	CDD:173686	99/280 (35%)
CG32944	NP_788574.3	STKc_Yank1	150..410	CDD:270730	93/264 (35%)