Protein Alignment AKT2 and trc

DIOPT Version :10

• Sequence 1: NP_001617.1
• Gene: AKT2 / 208
• HGNCID: 392
• Length: 481
• Species: Homo sapiens
• Sequence 2: NP_001262071.1
• Gene: trc / 40165
• FlyBaseID: FBgn0003744
• Length: 463
• Species: Drosophila melanogaster
• Alignment Length: 355
• Identity: 118/355 - (33%)
• Similarity: 180/355 - (50%)
• Gaps: 55/355 - (15%)

Human   144 RAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTR 208
            |.::.:.||:.||::|:|.||:|.||::|.||..||||:|||..::.|::|||...|..||....
  Fly    85 RLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEAD 149

Human   209 HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVY 273
            |.::..:.|:||....|..:||:..||::...|.::...:||..:||.:|...|::.:|....::
  Fly   150 HQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGFIH 214

Human   274 RDIKLENLMLDKDGHIKITDFGLC----KEGISD--------------GATMKTFC--------- 311
            ||||.:||:||..||:|::|||||    |...:|              |......|
  Fly   215 RDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYRDLSQAKPSDFIGTCASLSCSPMDSKRRA 279

Human   312 ---------------GTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFEL 361
                           |||:|:||||.....||.|.|||.|||:||||:.|..||.:.:.:..:..
  Fly   280 ESWKRNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRK 344

Human   362 IL--MEEIRFPR--TLSPEAKSLLAGLLKKDPKQRLGG--GPSDAKEVMEHRFFLSINWQDVVQK 420
            ::  .|.:.||.  .:|.|||..:.... .:..:|||.  |..|.|.|   .||..::|:.:.::
  Fly   345 VMNWRETLIFPPEIPISEEAKETIINFC-CEADRRLGSQRGLEDLKSV---PFFRGVDWEHIRER 405

Human   421 KLLPPFKPQVTSEVDTRYFDDEFTAQSITI 450
            ....|.  :|.|..||..| |||...|:.|
  Fly   406 PAAIPV--EVRSIDDTSNF-DEFPDVSLEI 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AKT2	NP_001617.1	PH_PKB	4..111	CDD:269947
		STKc_PKB_beta	156..478	CDD:173686	114/343 (33%)
trc	NP_001262071.1	MobB_Trc-like	24..88	CDD:439274	1/2 (50%)
		STKc_NDR_like	91..455	CDD:270750	117/349 (34%)