Protein Alignment AKT2 and akt2

DIOPT Version :10

• Sequence 1: NP_001617.1
• Gene: AKT2 / 208
• HGNCID: 392
• Length: 481
• Species: Homo sapiens
• Sequence 2: NP_937789.1
• Gene: akt2 / 378972
• ZFINID: ZDB-GENE-031007-5
• Length: 479
• Species: Danio rerio
• Alignment Length: 481
• Identity: 414/481 - (86%)
• Similarity: 444/481 - (92%)
• Gaps: 2/481 - (0%)

Human     1 MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMKT 65
            |||:||::|||||||||||||||||||:||||||||||||:||..|...||||||||||||||||
Zfish     1 MNEISVVREGWLHKRGEYIKTWRPRYFILKSDGSFIGYKEKPETSDANQPPLNNFSVAECQLMKT 65

Human    66 ERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPMDYKCGSPSDS 130
            |||||||||||||||||||||||||||..|||||:||||.|||.||.|.. ::|||...|||.|:
Zfish    66 ERPRPNTFVIRCLQWTTVIERTFHVDSNSEREEWIRAIQAVANGLKSREE-DEPMDINFGSPGDN 129

Human   131 STTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVA 195
            | .|.||.|::|:|.||||:|||||||||||||||||||||||||.|||||||||||||||||||
Zfish   130 S-LEGMEAAITKSRTKVTMSDFDYLKLLGKGTFGKVILVREKATGMYYAMKILRKEVIIAKDEVA 193

Human   196 HTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIV 260
            ||:|||||||||||||||.|||||||.|||||||||||||||||||||||||||:||||||||||
Zfish   194 HTITESRVLQNTRHPFLTTLKYAFQTRDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIV 258

Human   261 SALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDN 325
            ||||||||:||||||:|||||||||||||||||||||||||::.|||||||||||||||||||||
Zfish   259 SALEYLHSKDVVYRDLKLENLMLDKDGHIKITDFGLCKEGITNEATMKTFCGTPEYLAPEVLEDN 323

Human   326 DYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPK 390
            ||||||||||||||||||||||||||||||||||||||||||||||.||||||:|||||||||||
Zfish   324 DYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRNLSPEAKALLAGLLKKDPK 388

Human   391 QRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDR 455
            |||||||.||||||.|:||.::|||||:||||:||||||||||.||||||||||||:||:||||:
Zfish   389 QRLGGGPEDAKEVMTHKFFNNMNWQDVLQKKLVPPFKPQVTSETDTRYFDDEFTAQTITVTPPDQ 453

Human   456 YDSLGLLELDQRTHFPQFSYSASIRE 481
            ||||...:.|.||||.|||||||:||
Zfish   454 YDSLDAEDPDTRTHFSQFSYSASVRE 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AKT2	NP_001617.1	PH_PKB	4..111	CDD:269947	91/106 (86%)
		STKc_PKB_beta	156..478	CDD:173686	290/321 (90%)
akt2	NP_937789.1	PH_PKB	4..111	CDD:269947	91/106 (86%)
		STKc_PKB_beta	154..476	CDD:173686	290/321 (90%)