Protein Alignment AKT2 and gad8

DIOPT Version :10

• Sequence 1: NP_001617.1
• Gene: AKT2 / 208
• HGNCID: 392
• Length: 481
• Species: Homo sapiens
• Sequence 2: NP_588010.1
• Gene: gad8 / 2539206
• PomBaseID: SPCC24B10.07
• Length: 569
• Species: Schizosaccharomyces pombe
• Alignment Length: 329
• Identity: 149/329 - (45%)
• Similarity: 216/329 - (65%)
• Gaps: 6/329 - (1%)

Human   147 VTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPF 211
            :|::.|:.||::|||:||||:.||::.|.|.||:|.::|..|:::.||.||:.|..||....:||
pombe   225 LTIDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQVNNPF 289

Human   212 LTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDI 276
            :..||::||:..:|..|:.:.||||||.||.||..|...||:||.||::.|||.||..:|:|||:
pombe   290 IVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLHEFNVIYRDL 354

Human   277 KLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 341
            |.||::||..|||.:.||||||..::......||||||||||||:|..:.|.:.||||.|||::|
pombe   355 KPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAPELLLGHGYTKVVDWWTLGVLLY 419

Human   342 EMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEH 406
            ||:.|..|||:::...::..||.:.:|||..:..:||.||:|||.:.|::|||.|  .|:|:..|
pombe   420 EMITGLPPFYDENINEMYRKILQDPLRFPDNIDEKAKDLLSGLLTRAPEKRLGSG--GAQEIKNH 482

Human   407 RFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFP 471
            .||..|:|:.:..||:.|||||.|.|.:||..||.|||::    .|.|...:...|....:..|.
pombe   483 PFFDDIDWKKLCAKKIQPPFKPSVESAIDTSNFDSEFTSE----IPMDSVVADSHLSETVQQRFA 543

Human   472 QFSY 475
            .:||
pombe   544 NWSY 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AKT2	NP_001617.1	PH_PKB	4..111	CDD:269947
		STKc_PKB_beta	156..478	CDD:173686	146/320 (46%)
gad8	NP_588010.1	YPK1_N_like	66..225	CDD:212165	149/329 (45%)
		STKc_YPK1_like	235..547	CDD:270737	143/317 (45%)