Sequence 1: | NP_150087.1 | Gene: | Srebf2 / 20788 | MGIID: | 107585 | Length: | 1130 | Species: | Mus musculus |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001245436.1 | Gene: | Mitf / 3885647 | FlyBaseID: | FBgn0263112 | Length: | 837 | Species: | Drosophila melanogaster |
Alignment Length: | 527 | Identity: | 101/527 - (19%) |
---|---|---|---|
Similarity: | 188/527 - (35%) | Gaps: | 172/527 - (32%) |
- Green bases have known domain annotations that are detailed below.
Mouse 52 SSFPGGGSNGGSGNNSSGRGNNGGATDPAVQRSFSQVPLSTF--SPSAASPQAPALQVKVSPTPP 114
Mouse 115 RATPVLQPRPQPQPQPPAQLQQQTVMITPTFSTAPQTRIIQQP--LIYQNAATSFQVLQPQVQSL 177
Mouse 178 VTSP-----------QVQPVTIQQQV-------------QTVQAQRVLTQTANGTLQTLAPATVQ 218
Mouse 219 TVAAPQVQQV-PVLVQPQ-----------------IIKTDSLVLTTLKTDG--SPVMAAVQNPAL 263
Mouse 264 TALTAPIQTAALQVPTLVGSNGTILTTMPVMMG---------QEKVPIKQVPGGVKQLDP---PK 316
Mouse 317 EGERRTTHNIIEKRYRSSINDKIIELKDLV-MGTDA--------KMHKSGVLRKAIDYIKYLQQV 372
Mouse 373 NHKLRQENM---VLKLANQKNKLLKGIDLGSLVDSDVDLKIDDFNQNVLL--------------- 419
Mouse 420 -----MSPPASDS-----------------GSQAGFSPYSIDS---------EPGSPLLDD-AKV 452
Mouse 453 KDEPDSP 459 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Srebf2 | NP_150087.1 | Transcriptional activation (acidic). /evidence=ECO:0000250|UniProtKB:P36956 | 1..50 | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 53..133 | 14/81 (17%) | |||
Interaction with LMNA. /evidence=ECO:0000269|PubMed:11929849 | 226..480 | 65/325 (20%) | |||
HLH | 320..370 | CDD:278439 | 22/58 (38%) | ||
Leucine-zipper | 369..390 | 6/23 (26%) | |||
Mitf | NP_001245436.1 | MITF_TFEB_C_3_N | <272..>311 | CDD:292573 | 14/46 (30%) |
HLH | 505..570 | CDD:238036 | 23/64 (36%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1708 |
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.940 |